Endovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial

A Sarraj, MG Abraham, AE Hassan, S Blackburn… - The Lancet, 2024 - thelancet.com
Background Multiple randomised trials have shown efficacy and safety of endovascular
thrombectomy in patients with large ischaemic stroke. The aim of this study was to evaluate …

Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial

SB Coutts, S Ankolekar, R Appireddy, JF Arenillas… - The Lancet, 2024 - thelancet.com
Background Individuals with minor ischaemic stroke and intracranial occlusion are at
increased risk of poor outcomes. Intravenous thrombolysis with tenecteplase might improve …

A Randomized Controlled Trial of Tenecteplase Versus Standard of Care for Minor Ischemic Stroke with Proven Occlusion (TEMPO-2): Rational and design of a …

N Singh, CC Kenney, KS Butcher… - … Journal of Stroke, 2024 - journals.sagepub.com
Background: Almost half of acute ischemic stroke patients present with mild symptoms and
there are large practice variations in their treatment globally. Individuals with an intracranial …

The feasibility of the adapted H-GRASP program for perceived and actual daily-life upper limb activity in the chronic phase post-stroke

B Essers, JM Veerbeek, AR Luft… - Disability and …, 2024 - Taylor & Francis
Abstract (Purpose: Assessing feasibility and initial impact of the Home-Graded Repetitive
Arm Supplementary Program combined with in-home accelerometer-based feedback (AH …

The impact of frailty on short-term prognosis in discharged adult stroke patients: A multicenter prospective cohort study

H He, M Liu, L Li, Y Zheng, Y Nie, LD Xiao, Y Li… - International Journal of …, 2024 - Elsevier
Background Frailty is commonly observed in stroke patients and it is associated with
adverse outcomes. However, there remains a gap in longitudinal studies investigating the …

Reliability of study endpoint adjudication in a pragmatic trial on brain arteriovenous malformations

TE Darsaut, A Benomar, E Magro, JC Gentric… - Neurochirurgie, 2024 - Elsevier
Background The results of a clinical trial are given in terms of primary and secondary
outcomes that are obtained for each patient. Just as an instrument should provide the same …

Prognostic value of early EEG abnormalities in severe stroke patients requiring mechanical ventilation: a pre-planned analysis of the SPICE prospective multicenter …

S Benghanem, N Kubis, E Gayat, A Loiodice… - Critical Care, 2024 - Springer
Introduction Prognostication of outcome in severe stroke patients necessitating invasive
mechanical ventilation poses significant challenges. The objective of this study was to …

Transitioning to home and beyond following stroke: a prospective cohort study of outcomes and needs

G O'Callaghan, M Fahy, S O'Meara, M Chawke… - BMC Health Services …, 2024 - Springer
Introduction Understanding of the needs of people with stroke at hospital discharge and in
the first six-months is limited. This study aim was to profile and document the needs of …

[HTML][HTML] A randomised, double blind, placebo-controlled trial of a two-week course of dexamethasone for adult patients with a symptomatic Chronic Subdural …

PJ Hutchinson, E Edlmann, JG Hanrahan… - Health Technology …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Chronic subdural haematoma is a collection of'old blood'and its breakdown
products in the subdural space and predominantly affects older people. Surgical evacuation …

An automated flowchart for the Modified Rankin Scale assessment: A multicenter inter-rater agreement analysis

JB C de Andrade, TJ Quinn… - … Journal of Stroke, 2024 - journals.sagepub.com
Background and objective: The Modified Rankin Scale (mRS) is a widely adopted scale for
assessing stroke recovery. Despite limitations, the mRS has been adopted as primary …