Phylogenetic framework to explore trait evolution in Trypanosomatidae

AY Kostygov, ATS Albanaz, A Butenko… - Trends in …, 2024 - cell.com
The number of sequenced trypanosomatid genomes has reached a critical point so that they
are now available for almost all genera and subgenera. Based on this, we inferred a …

[HTML][HTML] Integrated genomics provides insights into the evolution of the polyphosphate accumulation trait of Ca. Accumulibacter

X Xie, X Deng, L Chen, J Yuan, H Chen, C Wei… - Environmental Science …, 2024 - Elsevier
Candidatus Accumulibacter, a prominent polyphosphate-accumulating organism (PAO) in
wastewater treatment, plays a crucial role in enhanced biological phosphorus removal …

Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites

JL Reis-Cunha, SA Pimenta-Carvalho… - Genome …, 2024 - genome.cshlp.org
Aneuploidy is widely observed in both unicellular and multicellular eukaryotes, usually
associated with adaptation to stress conditions. Chromosomal duplication stability is a …

Genome-wide distribution of 5-hydroxymethyluracil and chromatin accessibility in the Breviolum minutum genome

GK Marinov, X Chen, MP Swaffer, T Xiang… - Genome Biology, 2024 - Springer
Background In dinoflagellates, a unique and extremely divergent genomic and nuclear
organization has evolved. The highly unusual features of dinoflagellate nuclei and genomes …

In silico prediction of the metabolism of Blastocrithidia nonstop, a trypanosomatid with non-canonical genetic code

FR Opperdoes, K Záhonová, I Škodová-Sveráková… - Bmc Genomics, 2024 - Springer
Background Almost all extant organisms use the same, so-called canonical, genetic code
with departures from it being very rare. Even more exceptional are the instances when a …

Unwrap RAP1's Mystery at Kinetoplastid Telomeres

B Li - Biomolecules, 2024 - mdpi.com
Although located at the chromosome end, telomeres are an essential chromosome
component that helps maintain genome integrity and chromosome stability from protozoa to …

Protein phosphatase PP1 regulation of RNA polymerase II transcription termination and allelic exclusion of VSG genes in trypanosomes

R Kieft, Y Zhang, H Yan, RJ Schmitz… - Nucleic Acids …, 2024 - academic.oup.com
The genomes of Leishmania and trypanosomes are organized into polycistronic
transcription units flanked by a modified DNA base J involved in promoting RNA polymerase …

Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru (II) Ferrocenyl Derivatives with Two Different Bioactive Ligands

F Rivas, C Del Mármol, G Scalese… - Inorganic …, 2024 - ACS Publications
Human African trypanosomiasis (HAT, sleeping sickness) and American trypanosomiasis
(Chagas disease) are endemic zoonotic diseases caused by genomically related …

Characterization of Tau95 led to the identification of a four-subunit TFIIIC complex in trypanosomatid parasites

F Mondragón-Rosas, LE Florencio-Martínez… - Applied Microbiology …, 2024 - Springer
Abstract RNA polymerase III (RNAP III) synthetizes small essential non-coding RNA
molecules such as tRNAs and 5S rRNA. In yeast and vertebrates, RNAP III needs general …

Exploring the Genetic Landscape of Tilia Spp. with Molecular and Statistical Tools

AM Tenche-Constantinescu, DV Lalescu, S Popescu… - Horticulturae, 2024 - mdpi.com
Tree species with high ecological plasticity are recommended for use in urban green
infrastructures. This study explores the genetic diversity of Tilia cordata, Tilia platyphyllos …