Cryptosporidium parasites replicate within intestinal epithelial cells and are an important
cause of diarrhoeal disease in young children and in patients with primary and acquired …

Highlights•Autoimmune diseases impact more women than men and are underrepresented
in research.•Imbalance of T-cell populations is inherent to most autoimmune …

Immune exhaustion corresponds to a loss of effector function of T cells that associates with
cancer or chronic infection. Here, our objective was to decipher the mechanisms involved in …

Introduction Variant pseudorabies virus (PRV) is a newly emerged zoonotic pathogen that
can cause human blindness. PRV can take advantage of its large genome and multiple non …

Chronic viral infections cause T cell dysfunction in both animal models and human clinical
settings, thereby affecting the ability of the host immune system to clear viral pathogens and …

Poxviruses gained international attention due to the sharp rise in monkeypox cases in recent
years, highlighting the urgent need for the development of a secure and reliable vaccine …

The two primary types of non-puerperal mastitis (NPM) are granulomatous lobular mastitis
(GLM) and plasma cell mastitis (PCM). Existing research indicates that immune inflammatory …

Quercetin (3, 3′, 4′, 5, 7-pentahydroxyflavone) is a bioactive plant-derived flavonoid,
abundant in fruits and vegetables, that can effectively inhibit the growth of many types of …

IFN-I secretion provides a rapid host defense against infection with RNA viruses. Within the
host cell, viral RNA triggers the activation of the RIG-I signaling pathway, leading to the …

Background Altered expression and activity of solute carrier family 4 member 4 (SLC4A4)
could affect the growth, survival and metastasis of tumor cells. Currently, the role of SLC4A4 …