[HTML][HTML] Protein neddylation and its role in health and diseases
NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …
The neddylation inhibitor MLN4924 inhibits proliferation and triggers apoptosis of oral cancer cells but not for normal cells
YN Chen, YH Chan, JP Shiau… - Environmental …, 2024 - Wiley Online Library
Increased neddylation benefits the survival of several types of cancer cells. The inhibition of
neddylation has the potential to exert anticancer effects but is rarely assessed in oral cancer …
neddylation has the potential to exert anticancer effects but is rarely assessed in oral cancer …
[HTML][HTML] ncRNAs Orchestrate Chemosensitivity Induction by Neddylation Blockades
A Pérez-González, I Ramírez-Díaz, J Guzmán-Linares… - Cancers, 2024 - mdpi.com
Simple Summary Lung cancer is one of the leading cancers worldwide, with a poor
prognosis and high mortality. Recent studies show that epigenetic mechanisms such as …
prognosis and high mortality. Recent studies show that epigenetic mechanisms such as …