Enhancing fentanyl antinociception and preventing tolerance with α-2 adrenoceptor agonists in rats

DY Pehlivan, AY Kara, A Koyu, F Simsek - Behavioural Brain Research, 2024 - Elsevier
Fentanyl (FEN) is a potent opioid analgesic used for pain management. Opioid analgesic
tolerance poses a significant challenge to the clinical utility of opioid agonists. Preventing …