Toward diffusion tensor imaging as a biomarker in neurodegenerative diseases: technical considerations to optimize recordings and data processing
HP Müller, J Kassubek - Frontiers in Human Neuroscience, 2024 - frontiersin.org
Neuroimaging biomarkers have shown high potential to map the disease processes in the
application to neurodegenerative diseases (NDD), eg, diffusion tensor imaging (DTI). For …
application to neurodegenerative diseases (NDD), eg, diffusion tensor imaging (DTI). For …
Current potential diagnostic biomarkers of amyotrophic lateral sclerosis
Z Xu, R Xu - Reviews in the Neurosciences, 2024 - degruyter.com
Amyotrophic lateral sclerosis (ALS) currently lacks the useful diagnostic biomarkers. The
current diagnosis of ALS is mainly depended on the clinical manifestations, which …
current diagnosis of ALS is mainly depended on the clinical manifestations, which …
[HTML][HTML] Temporal and spatial progression of microstructural cerebral degeneration in ALS: A multicentre longitudinal diffusion tensor imaging study
Objective The corticospinal tract (CST) reveals progressive microstructural alterations in ALS
measurable by DTI. The aim of this study was to evaluate fractional anisotropy (FA) along …
measurable by DTI. The aim of this study was to evaluate fractional anisotropy (FA) along …
[HTML][HTML] Limbic Network and Papez Circuit Involvement in ALS: Imaging and Clinical Profiles in GGGGCC Hexanucleotide Carriers in C9orf72 and C9orf72-Negative …
F Christidi, J Kleinerova, EL Tan, S Delaney… - Biology, 2024 - ncbi.nlm.nih.gov
Background: While frontotemporal involvement is increasingly recognized in Amyotrophic
lateral sclerosis (ALS), the degeneration of limbic networks remains poorly characterized …
lateral sclerosis (ALS), the degeneration of limbic networks remains poorly characterized …
FlexDTI: flexible diffusion gradient encoding scheme-based highly efficient diffusion tensor imaging using deep learning
Z Wu, J Wang, Z Chen, Q Yang, Z Xing… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Most deep neural network-based diffusion tensor imaging methods require the
diffusion gradients' number and directions in the data to be reconstructed to match those in …
diffusion gradients' number and directions in the data to be reconstructed to match those in …
Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis
M Tahedl, EL Tan, J Kleinerova, S Delaney… - Neurology, 2024 - AAN Enterprises
Background and Objectives Amyotrophic lateral sclerosis (ALS) is predominantly associated
with motor cortex, corticospinal tract (CST), brainstem, and spinal cord degeneration, and …
with motor cortex, corticospinal tract (CST), brainstem, and spinal cord degeneration, and …
[HTML][HTML] Machine Learning and Brain-Computer Interface Approaches in Prognosis and Individualized Care Strategies for Individuals with Amyotrophic Lateral …
SYN Kew, SY Mok, CH Goh - MethodsX, 2024 - Elsevier
Amyotrophic lateral sclerosis (ALS) characterized by progressive degeneration of motor
neurons is a debilitating disease, posing substantial challenges in both prognosis and daily …
neurons is a debilitating disease, posing substantial challenges in both prognosis and daily …
[HTML][HTML] Harnessing Big Data in Amyotrophic Lateral Sclerosis: Machine Learning Applications for Clinical Practice and Pharmaceutical Trials
EL Tan, J Lope, P Bede - Journal of Integrative Neuroscience, 2024 - imrpress.com
The arrival of genotype-specific therapies in amyotrophic lateral sclerosis (ALS) signals the
dawn of precision medicine in motor neuron diseases (MNDs). After decades of academic …
dawn of precision medicine in motor neuron diseases (MNDs). After decades of academic …
Causal Associations Between Imaging-derived Phenotypes and Risk of Alzheimer's Disease and Other Neurodegenerative Disorders: A Mendelian Randomization …
Z Chen, J Liu, Y You - medRxiv, 2024 - medrxiv.org
Background Accumulating observational studies have suggested associations between
imaging-derived phenotypes (IDPs) and common neurodegenerative disorders, especially …
imaging-derived phenotypes (IDPs) and common neurodegenerative disorders, especially …
脊髓圆锥弥散张量成像扫描在下尿路功能障碍中的应用
孙浩瑜， 高轶， 吴娟， 廖利民， 靖华芳， 张思雨… - 中国康复理论与 …, 2024 - cjrtponline.com
目的利用MRI 弥散张量成像(DTI) 技术寻找膀胱过度活动症(OAB) 和膀胱活动低下(UAB)
患者脊髓圆锥信号的异常. 方法2021 年5 月至2023 年4 月, 从北京博爱医院招募下尿路功能 …
患者脊髓圆锥信号的异常. 方法2021 年5 月至2023 年4 月, 从北京博爱医院招募下尿路功能 …