Food safety, closely related to economic development of food industry and public health, has
become a global concern and gained increasing attention worldwide. Effective detection …

Infectious diseases continue to present significant challenges globally, with high mortality
rates and escalating healthcare costs. The Clustered Regularly Interspaced Short …

CRISPR–Cas12f nucleases are currently one of the smallest genome editors, exhibiting
advantages for efficient delivery via cargo-size-limited adeno-associated virus delivery …

In 2012, it was discovered that precise gene editing could be induced in target DNA using
the reprogrammable characteristics of the CRISPR system. Since then, several studies have …

Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas enzymes have
been widely applied for biosensor development, combined with various isothermal …

CRISPR-Cas systems and IS200/IS605 transposon-associated TnpBs have been utilized for
the development of genome editing technologies. Using bioinformatics analysis and …

The miniature VF CRISPR-Cas12f system has been repurposed for gene editing and
transcription modulation. The small size of Cas12f satisfies the packaging capacity of adeno …

The CRISPR/Cas system, an innovative gene-editing tool, is emerging as a promising
technique for genome modifications. This straightforward technique was created based on …

A plethora of CRISPR effectors, such as Cas3, Cas9, and Cas12a, are commonly employed
as gene editing tools. Among these, Cas12 effectors developed based on Class II type V …

Cas9 and Cas12 nucleases of class 2 CRISPR-Cas systems provide immunity in
prokaryotes through RNA-guided cleavage of foreign DNA. Here we characterize a set of …