Putative Roles and Therapeutic Potential of the Chaperone System in Amyotrophic Lateral Sclerosis and Multiple Sclerosis
L Noori, V Saqagandomabadi, V Di Felice, S David… - Cells, 2024 - mdpi.com
The putative pathogenic roles and therapeutic potential of the chaperone system (CS) in
amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are reviewed to provide a …
amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are reviewed to provide a …
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration
R San Gil, D Pascovici, J Venturato… - Nature …, 2024 - nature.com
Understanding the mechanisms that drive TDP-43 pathology is integral to combating
amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD) and other …
amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD) and other …
[HTML][HTML] Reversal of cognitive deficits in FUSR521G amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat …
MC Pelaez, F Fiore, N Larochelle, A Dabbaghizadeh… - …, 2024 - Elsevier
Protein misfolding and mislocalization are common to both familial and sporadic forms of
amyotrophic lateral sclerosis (ALS). Maintaining proteostasis through induction of heat …
amyotrophic lateral sclerosis (ALS). Maintaining proteostasis through induction of heat …
[HTML][HTML] Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS
MF Comaduran, S Minotti, S Jacob-Tomas… - Cell Stress and …, 2024 - Elsevier
Protein misfolding and mislocalization are common themes in neurodegenerative disorders,
including motor neuron disease, and amyotrophic lateral sclerosis (ALS). Maintaining …
including motor neuron disease, and amyotrophic lateral sclerosis (ALS). Maintaining …