Employing Informatics Strategies in Alzheimer's Disease Research: A Review from Genetics, Multiomics, and Biomarkers to Clinical Outcomes

J Bao, BN Lee, J Wen, M Kim, S Mu… - Annual Review of …, 2024 - annualreviews.org
Alzheimer's disease (AD) is a critical national concern, affecting 5.8 million people and
costing more than 250 billion annually. However, there is no available cure. Thus, effective …

Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally

JP Yuan, SM Coury, TC Ho, IH Gotlib - Neuropsychopharmacology, 2024 - nature.com
Elevated levels of systemic inflammation are associated with altered reward-related brain
function in ventral striatal areas of the brain like the nucleus accumbens (NAcc). In …

[HTML][HTML] Unraveling how the adolescent brain deals with criticism using dynamic causal modeling

Q Chen, SLB Bonduelle, GR Wu, MA Vanderhasselt… - NeuroImage, 2024 - Elsevier
Sensitivity to criticism, which can be defined as a negative evaluation that a person receives
from someone else, is considered a risk factor for the development of psychiatric disorders in …

Perception of social inclusion/exclusion and response inhibition in adolescents with past suicide attempt: a multidomain task-based fMRI study

AJ Gifuni, F Pereira, MM Chakravarty, M Lepage… - Molecular …, 2024 - nature.com
The occurrence of suicidal behaviors increases during adolescence. Hypersensitivity to
negative social signals and deficits in cognitive control are putative mechanisms of suicidal …

Multivariate association between psychosocial environment, behaviors, and brain functional networks in adolescent depression

Y Gao, R Feng, X Ouyang, Z Zhou, W Bao, Y Li… - Asian Journal of …, 2024 - Elsevier
Background Adolescent depression shows high clinical heterogeneity. Brain functional
networks serve as a powerful tool for investigating neural mechanisms underlying …

[HTML][HTML] Vicarious punishment of moral violations in naturalistic drama narratives predicts cortical synchronization

R Weber, FR Hopp, A Eden, JT Fisher, HE Lee - NeuroImage, 2024 - Elsevier
Punishment of moral norm violators is instrumental for human cooperation. Yet, social and
affective neuroscience research has primarily focused on second-and third-party norm …

Mnemonic but not contextual feedback signals defy dedifferentiation in the aging early visual cortex

I Ehrlich, J Ortiz-Tudela, YY Tan, L Muckli… - Journal of …, 2024 - Soc Neuroscience
Perception is an intricate interplay between feedforward visual input and internally
generated feedback signals that comprise concurrent contextual and time-distant mnemonic …

[HTML][HTML] Intersubject correlations in reward and mentalizing brain circuits separately predict persuasiveness of two types of ISIS video propaganda

MS Cohen, YC Leong, K Ruby, RA Pape, J Decety - Scientific reports, 2024 - nature.com
The Islamist group ISIS has been particularly successful at recruiting Westerners as
terrorists. A hypothesized explanation is their simultaneous use of two types of propaganda …

Cerebellum and social abilities: A structural and functional connectivity study in a transdiagnostic sample

Y Kong, M Roser, I Bègue, Y Elandaloussi… - Human Brain …, 2024 - Wiley Online Library
The cerebellum has been involved in social abilities and autism. Given that the cerebellum
is connected to the cortex via the cerebello‐thalamo‐cortical loop, the connectivity between …

[HTML][HTML] The human hypothalamus coordinates switching between different survival actions

J Kim, SM Tashjian, D Mobbs - PLoS biology, 2024 - journals.plos.org
Comparative research suggests that the hypothalamus is critical in switching between
survival behaviors, yet it is unclear if this is the case in humans. Here, we investigate the role …