Employing Informatics Strategies in Alzheimer's Disease Research: A Review from Genetics, Multiomics, and Biomarkers to Clinical Outcomes
Alzheimer's disease (AD) is a critical national concern, affecting 5.8 million people and
costing more than 250 billion annually. However, there is no available cure. Thus, effective …
costing more than 250 billion annually. However, there is no available cure. Thus, effective …
Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally
Elevated levels of systemic inflammation are associated with altered reward-related brain
function in ventral striatal areas of the brain like the nucleus accumbens (NAcc). In …
function in ventral striatal areas of the brain like the nucleus accumbens (NAcc). In …
[HTML][HTML] Unraveling how the adolescent brain deals with criticism using dynamic causal modeling
Sensitivity to criticism, which can be defined as a negative evaluation that a person receives
from someone else, is considered a risk factor for the development of psychiatric disorders in …
from someone else, is considered a risk factor for the development of psychiatric disorders in …
Perception of social inclusion/exclusion and response inhibition in adolescents with past suicide attempt: a multidomain task-based fMRI study
The occurrence of suicidal behaviors increases during adolescence. Hypersensitivity to
negative social signals and deficits in cognitive control are putative mechanisms of suicidal …
negative social signals and deficits in cognitive control are putative mechanisms of suicidal …
Multivariate association between psychosocial environment, behaviors, and brain functional networks in adolescent depression
Y Gao, R Feng, X Ouyang, Z Zhou, W Bao, Y Li… - Asian Journal of …, 2024 - Elsevier
Background Adolescent depression shows high clinical heterogeneity. Brain functional
networks serve as a powerful tool for investigating neural mechanisms underlying …
networks serve as a powerful tool for investigating neural mechanisms underlying …
[HTML][HTML] Vicarious punishment of moral violations in naturalistic drama narratives predicts cortical synchronization
Punishment of moral norm violators is instrumental for human cooperation. Yet, social and
affective neuroscience research has primarily focused on second-and third-party norm …
affective neuroscience research has primarily focused on second-and third-party norm …
Mnemonic but not contextual feedback signals defy dedifferentiation in the aging early visual cortex
I Ehrlich, J Ortiz-Tudela, YY Tan, L Muckli… - Journal of …, 2024 - Soc Neuroscience
Perception is an intricate interplay between feedforward visual input and internally
generated feedback signals that comprise concurrent contextual and time-distant mnemonic …
generated feedback signals that comprise concurrent contextual and time-distant mnemonic …
[HTML][HTML] Intersubject correlations in reward and mentalizing brain circuits separately predict persuasiveness of two types of ISIS video propaganda
The Islamist group ISIS has been particularly successful at recruiting Westerners as
terrorists. A hypothesized explanation is their simultaneous use of two types of propaganda …
terrorists. A hypothesized explanation is their simultaneous use of two types of propaganda …
Cerebellum and social abilities: A structural and functional connectivity study in a transdiagnostic sample
Y Kong, M Roser, I Bègue, Y Elandaloussi… - Human Brain …, 2024 - Wiley Online Library
The cerebellum has been involved in social abilities and autism. Given that the cerebellum
is connected to the cortex via the cerebello‐thalamo‐cortical loop, the connectivity between …
is connected to the cortex via the cerebello‐thalamo‐cortical loop, the connectivity between …
[HTML][HTML] The human hypothalamus coordinates switching between different survival actions
Comparative research suggests that the hypothalamus is critical in switching between
survival behaviors, yet it is unclear if this is the case in humans. Here, we investigate the role …
survival behaviors, yet it is unclear if this is the case in humans. Here, we investigate the role …