Unmet needs in the post-DAA era: the risk and molecular mechanisms of hepatocellular carcinoma after HCV eradication

CF Huang, MH Awad, M Gal-Tanamy… - Clinical and Molecular …, 2024 - e-cmh.org
Hepatitis C virus (HCV) is one of the major etiologies of hepatocellular carcinoma with
approximately 30% of HCC being due to HCV infection worldwide. HCV eradication by …

[HTML][HTML] Contemporary Insights into Hepatitis C Virus: A Comprehensive Review

M Sallam, R Khalil - Microorganisms, 2024 - mdpi.com
Hepatitis C virus (HCV) remains a significant global health challenge. Approximately 50
million people were living with chronic hepatitis C based on the World Health Organization …

[HTML][HTML] Opportunistic treatment of hepatitis C infection among hospitalized people who inject drugs (OPPORTUNI-C): a stepped wedge cluster randomized trial

H Midgard, KB Malme, CM Pihl… - Clinical Infectious …, 2024 - academic.oup.com
Background We aimed to evaluate the efficacy of opportunistic treatment of hepatitis C virus
(HCV) infection among hospitalized people who inject drugs (PWID). Methods We …

[HTML][HTML] Long-term trends in incidence, mortality and burden of liver cancer due to specific etiologies in Hubei Province

H Liu, J Li, S Zhu, X Zhang, F Zhang, X Zhang… - Scientific Reports, 2024 - nature.com
Liver cancer, a chronic non-communicable disease, represents a serious public health
problem. Long-term trends in the burden of liver cancer disease are heterogeneous across …

Incidence of hepatitis C virus infection in the prison setting: The SToP‐C study

B Hajarizadeh, JM Carson, M Byrne… - Journal of Viral …, 2024 - Wiley Online Library
People in prison are at high risk of HCV given high injecting drug use prevalence. This study
evaluated HCV incidence and associated injecting drug use characteristics in prison. The …

[HTML][HTML] Prevalence of hepatitis C virus exposure and infection among Indigenous and tribal populations: a global systematic review and meta-analysis

S Elliott, E Flynn, S Mathew, B Hajarizadeh… - Public Health, 2024 - Elsevier
Objectives The objective of this study was to estimate prevalence of hepatitis C virus (HCV)
exposure and infection among Indigenous and tribal populations globally. Study design …

[HTML][HTML] No gender differences in the 24-month course of non-invasive liver fibrosis markers after DAA therapy in HCV-mono and HCV/HIV-coinfected patients

J Collazos, L Pérez-Is, B de la Fuente, L Morano… - Scientific Reports, 2024 - nature.com
Untreated HCV mono and HCV/HIV coinfected women have lower degrees of liver fibrosis
(LF) compared to men. Direct acting antiviral (DAA) therapy attains viral eradication in> 90 …

Comprehensive review of clinical presentation, diagnosis, management, and prognosis of ruptured hepatocellular carcinoma

H Aziz, YIC Kwon, A Park, Y Kwon, Y Aswani… - Journal of …, 2024 - Elsevier
Introduction Spontaneous rupture of hepatocellular carcinoma (rHCC) is a life-threatening
complication occurring in 3–15% of patients with HCC. This review discusses the most …

Electrochemical biosensor for sensitive detection of SARS-CoV-2 gene fragments using Bi2Se3 topological insulator

J Bai, Y Jiang, F Tan, P Zhu, X Li, X Xiong, Z Wang… - …, 2024 - Elsevier
In this study, we have designed an electrochemical biosensor based on topological material
Bi 2 Se 3 for the sensitive detection of SARS-CoV-2 in the COVID-19 pandemic. Flake …

[HTML][HTML] ViroISDC: a method for calling integration sites of hepatitis B virus based on feature encoding

L Qiao, C Li, W Lin, X He, J Mi, Y Tong, J Gao - BMC bioinformatics, 2024 - Springer
Abstract Background Hepatitis B virus (HBV) integrates into human chromosomes and can
lead to genomic instability and hepatocarcinogenesis. Current tools for HBV integration site …