Programmed death of macrophages in atherosclerosis: mechanisms and therapeutic targets

GRY De Meyer, M Zurek, P Puylaert… - Nature Reviews …, 2024 - nature.com
Atherosclerosis is a progressive inflammatory disorder of the arterial vessel wall
characterized by substantial infiltration of macrophages, which exert both favourable and …

Comprehensive view of macrophage autophagy and its application in cardiovascular diseases

W Pan, J Zhang, L Zhang, Y Zhang, Y Song… - Cell …, 2024 - Wiley Online Library
Cardiovascular diseases (CVDs) are the primary drivers of the growing public health
epidemic and the leading cause of premature mortality and economic burden worldwide …

Fatal attractions that trigger inflammation and drive atherosclerotic disease

H Sharma, K Mossman… - European Journal of …, 2024 - Wiley Online Library
Background Atherosclerosis is the salient, underlying cause of cardiovascular diseases,
such as arrhythmia, coronary artery disease, cardiomyopathy, pulmonary embolism and …

Role of sirtuins in attenuating plaque vulnerability in atherosclerosis

P Velpuri, V Rai, DK Agrawal - Molecular and Cellular Biochemistry, 2024 - Springer
Atherosclerosis is characterized by the development of intimal plaque, thrombosis, and
stenosis of the vessel lumen causing decreased blood flow and hypoxia precipitating …

[HTML][HTML] Inhibition of endoplasmic reticulum stress and excessive autophagy by Jiedu Tongluo Tiaogan Formula via a CaMKKβ/AMPK pathway contributes to protect …

Q Zhang, W Jin, H Wang, C Tang, X Zhao… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Jiedu Tongluo Tiaogan Formula (JTTF), a
traditional Chinese herbal decoction, exhibits the potential to treat type 2 diabetes mellitus …

Nattokinase attenuates endothelial inflammation through the activation of SRF and THBS1

HW Chiu, CL Chou, KT Lee, CC Shih, TH Huang… - International Journal of …, 2024 - Elsevier
Natto contains a potent fibrinolytic enzyme called nattokinase (NK), which has thrombolytic,
antihypertensive, antiatherosclerotic and lipid-lowering effects. Although NK has been …

Cell death in atherosclerosis

D Ni, C Lei, M Liu, J Peng, G Yi, Z Mo - Cell Cycle, 2024 - Taylor & Francis
ABSTRACT A complex and evolutionary process that involves the buildup of lipids in the
arterial wall and the invasion of inflammatory cells results in atherosclerosis. Cell death is a …

Reactive Carbonyl Species and Protein Lipoxidation in Atherogenesis

A Nègre-Salvayre, R Salvayre - Antioxidants, 2024 - mdpi.com
Atherosclerosis is a multifactorial disease of medium and large arteries, characterized by the
presence of lipid-rich plaques lining the intima over time. It is the main cause of …

Increased thyroid stimulating hormone (TSH) as a possible risk factor for atherosclerosis in subclinical hypothyroidism

BM Alomair, HM Al-Kuraishy, AI Al-Gareeb… - Thyroid Research, 2024 - Springer
Primary hypothyroidism (PHT) is associated with an increased risk for the development of
atherosclerosis (AS) and other cardiovascular disorders. PHT induces atherosclerosis (AS) …

SGLT2 Inhibitors Extra Glycemic Potential: A Possible Novel Approach to the Prevention of Atherosclerotic Events

SC Wankumbu, J Xiao-Man, S Lukundo… - Asian Journal of Health …, 2024 - a-jhr.com
Introduction: Cardiovascular diseases are a major global health concern, with
atherosclerosis being a significant contributor. Diabetes mellitus is a well-known risk factor …