Pertussis vaccines, epidemiology and evolution

M Domenech de Cellès, P Rohani - Nature Reviews Microbiology, 2024 - nature.com
Pertussis, which is caused by Bordetella pertussis, has plagued humans for at least 800
years, is highly infectious and can be fatal in the unvaccinated, especially very young …

[HTML][HTML] Molecular Evolution and Increasing Macrolide Resistance of Bordetella pertussis, Shanghai, China, 2016–2022

P Fu, J Zhou, C Yang, Y Nijiati, L Zhou… - Emerging Infectious …, 2024 - ncbi.nlm.nih.gov
Resurgence and spread of macrolide-resistant Bordetella pertussis (MRBP) threaten global
public health. We collected 283 B. pertussis isolates during 2016–2022 in Shanghai, China …

Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis

J Gillard, M Suffiotti, P Brazda… - Nature …, 2024 - nature.com
Many countries continue to experience pertussis epidemics despite widespread vaccination.
Waning protection after booster vaccination has highlighted the need for a better …

Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations

P Kardos, J Correia de Sousa, U Heininger… - Human Vaccines & …, 2024 - Taylor & Francis
Pertussis has several notable consequences, causing economic burden, increased strain on
healthcare facilities, and reductions in quality of life. Recent years have seen a trend toward …

Whole-genome comparison of two same-genotype macrolide-resistant Bordetella pertussis isolates collected in Japan

K Koide, Y Uchitani, T Yamaguchi, N Otsuka, M Goto… - Plos one, 2024 - journals.plos.org
The emergence of macrolide-resistant Bordetella pertussis (MRBP) is a significant problem
because it reduces treatment options for pertussis and exacerbates the severity and spread …

[HTML][HTML] Using a dynamical model to study the impact of a toxoid vaccine on the evolution of a bacterium: The example of diphtheria

F Lecorvaisier, D Pontier, B Soubeyrand, D Fouchet - Ecological Modelling, 2024 - Elsevier
Vaccines are one of humankind's greatest weapons against infectious diseases. However,
their usefulness is often questioned and the public tends to distrust vaccines. A …

Rising Pertussis Cases and Deaths in China: Current Trends and Clinical Solutions

H Yahong, G Mengyang, Q Meng, D Yu… - Emerging Microbes & …, 2024 - Taylor & Francis
Over the past ten months, the number of reported pertussis cases in China rose from 1,512
in June 2023 to a significant spike in early 2024, reaching 15,275 cases in January. In the …

[HTML][HTML] Effect of oxidative stress on antigen productivity in B. Pertussis cultures

A Mishra, S Steinbach, IM Tamer, H Budman - Biochemical Engineering …, 2024 - Elsevier
Whooping cough, also known as pertussis, is an infectious respiratory disease caused by
Bordetella pertussis, a type of gram-negative, aerobic, pathogenic bacteria with a …

Bordetella pertussis

AD Caulfield, ET Harvill - Molecular Medical Microbiology, 2024 - Elsevier
Bordetella pertussis is the etiologic agent of whooping cough, a highly transmissible
respiratory disease that causes an estimated 24–48 million infections and 100,000–300,000 …

Pertussis upsurge, age shift and vaccine escape post-COVID-19 caused by ptxP3 macrolide-resistant Bordetella pertussis MT28 clone in China: a genomic …

P Fu, G Yan, Y Li, L Xie, Y Ke, S Qiu, S Wu, X Shi, J Qin… - medRxiv, 2024 - medrxiv.org
Background The upsurge of pertussis post-COVID-19 and expansion of macrolide-resistant
Bordetella pertussis (MRBP) pose significant public health challenges worldwide. China has …