Antifungal drug resistance in Candida: a special emphasis on amphotericin B

L Ahmady, M Gothwal, MM Mukkoli, VK Bari - APMIS, 2024 - Wiley Online Library
Invasive fungal infections in humans caused by several Candida species, increased
considerably in immunocompromised or critically ill patients, resulting in substantial …

Biomaterials with antifungal strategies to fight oral infections

J Allkja, M Roudbary, AMV Alves… - Critical Reviews in …, 2024 - Taylor & Francis
Oral fungal infections pose a threat to human health and increase the economic burden of
oral diseases by prolonging and complicating treatment. A cost-effective strategy is to try to …

Discovery of a novel antifungal agent: Allhydrocarbon stapling modification of peptide Aurein1. 2

M Zheng, H Chen, X Li, S Chen, Y Shi… - Journal of Peptide …, 2024 - Wiley Online Library
Aurein1. 2 is secreted by the Australian tree frog Litoria aurea and is active against a broad
range of infectious microbes including bacteria, fungi, and viruses. Its antifungal potency has …

Antifungal Tetrahydrocarbazole Compound CAR-8 Induces Endoplasmic Reticulum Stress in Candida albicans

W Chao, L Qiu, L Gao, J Feng, Y Liu, L Yan… - ACS Infectious …, 2024 - ACS Publications
The development of new effective antifungal agents is essential to combat fungal infections.
Tetrahydrocarbazole has been exploited as a promising skeleton against various …

Paracoccidioides spp.: the structural characterization of extracellular matrix, expression of glucan synthesis and associated genes and adhesins during biofilm …

LT Oliveira, CM Marcos, AKLF Cabral… - Frontiers in …, 2024 - frontiersin.org
The genus Paracoccidioides includes Paracoccidioides lutzii and the Paracoccidioides
brasiliensis complex, which comprises four phylogenetic species. A key feature …

Decoding the role of oxidative stress resistance and alternative carbon substrate assimilation in the mature biofilm growth mode of Candida glabrata

K Raj, D Paul, P Rishi, G Shukla, D Dhotre… - BMC microbiology, 2024 - Springer
Background Biofilm formation is viewed as a vital mechanism in C. glabrata pathogenesis.
Although, it plays a significant role in virulence but transcriptomic architecture and metabolic …

Bioinspired ferromagnetic NiFe2O4 nanoparticles: Eradication of fungal and drug-resistant bacterial pathogens and their established biofilm

MA Ansari, MN Alomary - Microbial Pathogenesis, 2024 - Elsevier
Nickel ferrite nanoparticles (NiFe 2 O 4 NPs) were synthesized using the medicinally
important plant Aloe vera leaf extract, and their structural, morphological, and magnetic …

[HTML][HTML] Potent anti-biofilm properties of plumbagin against fluconazole-resistant Candida auris

HW Jin, YB Eom - Journal of Traditional and Complementary Medicine, 2024 - Elsevier
Background and aim The escalation of fungal infections is driving an increase in disease
and mortality rates. In particular, the emergence of Candida auris (C. auris), which shows …

Computer-made peptide RQ18 acts as a dual antifungal and antibiofilm peptide though membrane-associated mechanisms of action

CV Almeida, CFR de Oliveira… - Archives of Biochemistry …, 2024 - Elsevier
The spread of fungi resistant to conventional drugs has become a threatening problem. In
this context, antimicrobial peptides (AMPs) have been considered as one of the main …

Biofilm formation by the fungus Phaeomoniella chlamydospora: a causal agent of esca disease of grapevine

Z Karácsony, N Molnár, D Szabó, N Bakos-Barczi… - Mycological …, 2024 - Springer
The present study suggests that the Esca pathogenic fungus Phaeomoniella chlamydospora
can form biofilm in vitro and possibly in the grapevine host tissues. This phenomenon was …