DNA Modifications: Biomarkers for the Exposome?
C Möller, J Virzi, YJ Chang, A Keidel, MR Chao… - Environmental …, 2024 - Elsevier
The concept of the exposome is the encompassing of all the environmental exposures, both
exogenous and endogenous, across the life course. Many, if not all, of these exposures can …
exogenous and endogenous, across the life course. Many, if not all, of these exposures can …
Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics
N Ragi, SJ Walmsley, FC Jacobs… - Chemical research in …, 2024 - ACS Publications
Air pollution, tobacco smoke, and red meat are associated with renal cell cancer (RCC) risk
in the United States and Western Europe; however, the chemicals that form DNA adducts …
in the United States and Western Europe; however, the chemicals that form DNA adducts …
DNA adductomics aided rapid screening of genotoxic impurities using nucleosides and 3D bioprinted human liver organoids
Y Li, C Xu, X Zhou, J Li, S Xu, Y Tu, X Mu, J Huang… - Talanta, 2024 - Elsevier
Current genotoxicity assessment methods are mainly employed to verify the genotoxic safety
of drugs, but do not allow for rapid screening of specific genotoxic impurities (GTIs). In this …
of drugs, but do not allow for rapid screening of specific genotoxic impurities (GTIs). In this …
Expanding Computational Resources for the Discovery of Molecular Biomarkers of Exposure
KJ Murray - 2024 - search.proquest.com
Recurrent exposure to genotoxic chemicals and other harmful environmental agents is
directly related to the development of adverse phenotypes, carcinogenesis, and …
directly related to the development of adverse phenotypes, carcinogenesis, and …