Exercise, stress, sleep and diet are four distinct but intertwined lifestyle factors that influence
the cardiovascular system. Abundant epidemiological, clinical and preclinical studies have …

Nutrition has broad impacts on all physiological processes. However, how nutrition affects
human immunity remains largely unknown. Here we explored the impact of a dietary …

Background Ketogenic diets (KD) have shown remarkable effects in many disease areas. It
has been demonstrated in numerous animal experiments that KD is effective in the treatment …

Dietary fasting markedly influences the distribution and function of immune cells and exerts
potent immunosuppressive effects. However, the mechanisms through which fasting …

Background Lipid metabolism has been implicated in a variety of normal cellular processes
and strongly related to the development of multiple diseases, including tumor. Tumor …

Introduction Maternal obesity poses risks for both mother and offspring during pregnancy,
with underlying mechanisms remaining largely unexplored. Obesity is associated with …

The gut and liver are recognized to mutually communicate through the biliary tract, portal
vein, and systemic circulation. However, it remains unclear how this gut-liver axis regulates …

Senoinflammation is characterized by an unresolved low-grade inflammatory process that
affects multiple organs and systemic functions. This review begins with a brief overview of …

Cells of the mammalian innate immune system have evolved to protect the host from various
environmental or internal insults and injuries which perturb the homeostatic state of the …

Dehydration and malnutrition are common and often underdiagnosed in hospital settings.
Multidrug-resistant bacterial infections result in more than 35,000 deaths a year in …