Diseases associated with chronic inflammation constitute a major health burden across the
world. As central instigators of the inflammatory response to infection and tissue damage …

The innate immune system initiates cell death pathways in response to pathogens and
cellular stress. Cell death can be either non-lytic (apoptosis) or lytic (PANoptosis, pyroptosis …

Alzheimer's disease (AD) is the seventh most common cause of mortality and one of the
major causes of disability and vulnerability in the elderly. AD is characterized by gradual …

Epilepsy is one of the most common serious chronic brain disorders, affecting up to 70
million people worldwide. Vascular disruption, including blood–brain barrier impairment and …

Abstract Despite effective antiretroviral therapies, 20–30% of persons with treated HIV
infection develop a neurodegenerative syndrome termed HIV-associated neurocognitive …

Adipose tissue has recently been recognized as an important endocrine organ that plays a
crucial role in energy metabolism and in the immune response in many metabolic tissues …

Pyroptosis, an inflammatory programmed cell death process, has recently garnered
significant attention due to its pivotal role in various neurological diseases. This review …

Background Alzheimer's disease (AD) is the most common neurodegenerative disorder
affecting memory and cognition. The disease is accompanied by an abnormal deposition of …

Multiple sclerosis (MS) is a chronic disease that is characterized by demyelination and
neuronal damage. Experimental autoimmune encephalomyelitis (EAE) mice are used to …

Every year, 10 million people develop dementia, the most common of which is Alzheimer's
disease (AD). To date, there is no way to prevent cognitive decline and therapies are limited …