Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues
Lipid nanoparticles (LNPs) largely rely on ionizable lipids to yield successful nucleic acid
delivery via electrostatic disruption of the endosomal membrane. Here, we report the …
delivery via electrostatic disruption of the endosomal membrane. Here, we report the …
Bacteriophages as nanocarriers for targeted drug delivery and enhanced therapeutic effects
SC Emencheta, AL Onugwu, CF Kalu, PN Ezinkwo… - Materials …, 2024 - pubs.rsc.org
The effective delivery of therapeutic agents is as important as the active therapeutic agent
because it may make or mar the outcome. Traditional/conventional drug delivery systems …
because it may make or mar the outcome. Traditional/conventional drug delivery systems …
Recent Progress in Nucleic Acid Pulmonary Delivery toward Overcoming Physiological Barriers and Improving Transfection Efficiency
Q Wang, C Bu, Q Dai, J Chen, R Zhang… - Advanced …, 2024 - Wiley Online Library
Pulmonary delivery of therapeutic agents has been considered the desirable administration
route for local lung disease treatment. As the latest generation of therapeutic agents, nucleic …
route for local lung disease treatment. As the latest generation of therapeutic agents, nucleic …
Carbon nanotubes functionalized with α-aminoisobutyric acid-containing peptide increase gene delivery efficiency in plant mitochondria
SSY Law, M Kuzumoto, S Fujita, T Fujigaya… - Polymer Journal, 2024 - nature.com
Functionalized carbon nanotubes have shown tremendous promise in the field of plant
biotechnology for genetic engineering and cargo delivery; recent findings have shown that …
biotechnology for genetic engineering and cargo delivery; recent findings have shown that …
Phage Display Identified Novel Leydig Cell Homing Peptides for Testicular Targeting
Y Jirwankar, A Nair, S Marathe… - ACS Pharmacology & …, 2024 - ACS Publications
Conventional drug delivery methods to treat testicular disorders face various challenges,
which could be circumvented by using targeted drug delivery. Testicular cell targeting …
which could be circumvented by using targeted drug delivery. Testicular cell targeting …
[HTML][HTML] Nanocarriers for inhaled delivery of RNA therapeutics
SG Huayamares, R Zenhausern, D Loughrey - Current Research in …, 2024 - Elsevier
RNA therapeutics are promising for the treatment of lung diseases where small molecules
and biologics have failed to have much success in the past. While siRNA and mRNA drugs …
and biologics have failed to have much success in the past. While siRNA and mRNA drugs …
Synthetic mucus barrier arrays as a nanoparticle formulation screening platform
A mucus gel layer lines the luminal surface of tissues throughout the body to protect them
from infectious agents and particulates. As a result, nanoparticle drug delivery systems …
from infectious agents and particulates. As a result, nanoparticle drug delivery systems …
[PDF][PDF] Current Research in Biotechnology
SG Huayamares, MP Lokugamage… - Current Research in …, 2024 - researchgate.net
ABSTRACT RNA therapeutics are promising for the treatment of lung diseases where small
molecules and biologics have failed to have much success in the past. While siRNA and …
molecules and biologics have failed to have much success in the past. While siRNA and …