Abstract The imprinted Dlk1-Dio3 domain comprises the developmental genes Dlk1 and
Rtl1, which are silenced on the maternal chromosome in different cell types. On this parental …

The microenvironment and cell populations within the myometrium play crucial roles in
maintaining uterine structural integrity and protecting the fetus during pregnancy. However …

Background Placenta accreta spectrum disorders are associated with severe maternal
morbidity and mortality. Placenta accreta spectrum disorders involve excessive adherence …

The placenta is a unique organ for ensuring normal embryonic growth in the uterine. Here,
we found that maternal RNA transcription in Dlk1-Dio3 imprinted domain is essential for …

Fanconi anemia (FA) is a genetically and clinically heterogenous inherited disorder.
Clinically, Fanca subtype patients exhibited milder phenotypes compared to Fancd2 …

Victims of a radiation terrorist event will include pregnant women and unborn fetuses.
Mitochondrial dysfunction and oxidative stress are key pathogenic factors of fetal irradiation …

Pregnancy is a unique situation, in which two (or more) individuals are in intimate contact,
with development of the foetus supported by a specialised structure called the placenta. The …

Fetal-originated diseases refer to birth defects of offspring and multiple chronic diseases in
adulthood caused by abnormal embryonic development. However, due to the vulnerability of …

Migraine is a complex neurological disorder with its cause most likely stemming from
polygenic and environmental factors (Aczél et al., 2021; Vetvik & MacGregor, 2021) …

Thesis template of the University of Helsinki Page 1 Association of DNA methylation at the
imprinted DLK1- DIO3 locus in placenta with assisted reproductive technology and subfertility …