COVID-19 and bone loss: a review of risk factors, mechanisms, and future directions

A Creecy, OD Awosanya, A Harris, X Qiao… - Current Osteoporosis …, 2024 - Springer
Abstract Purpose of Review SARS-CoV-2 drove the catastrophic global phenomenon of the
COVID-19 pandemic resulting in a multitude of systemic health issues, including bone loss …

SARS-CoV-2 and its multifaceted impact on bone health: mechanisms and clinical evidence

A Harris, A Creecy, OD Awosanya, T McCune… - Current Osteoporosis …, 2024 - Springer
Abstract Purpose of Review SARS-CoV-2 infection, the culprit of the COVID-19 pandemic,
has been associated with significant long-term effects on various organ systems, including …

[HTML][HTML] Targeting gut microbiota in osteoporosis: Impact of the microbial-based functional food ingredients

P Duffuler, KS Bhullar, J Wu - Food Science and Human Wellness, 2024 - Elsevier
Osteoporosis is the most common bone disorder, characterized by low bone mineral density
and microarchitectural deterioration of the bone tissue, which increases the susceptibility to …

Rheumatoid arthritis molecular targets and their importance to flavonoid‐based therapy

AT Rufino, M Freitas, C Proença… - Medicinal Research …, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is a progressive, chronic, autoimmune, inflammatory, and systemic
condition that primarily affects the synovial joints and adjacent tissues, including bone …

[HTML][HTML] IL-17 and IL-21: their immunobiology and therapeutic potentials

CH Koh, BS Kim, CY Kang, Y Chung, H Seo - Immune Network, 2024 - ncbi.nlm.nih.gov
Studies over the last 2 decades have identified IL-17 and IL-21 as key cytokines in the
modulation of a wide range of immune responses. IL-17 serves as a critical defender against …

CD4+ and CD8+ T cells reduce inflammation and promote bone healing in response to titanium implants

D Avery, L Morandini, L Sheakley, M Grabiec… - Acta Biomaterialia, 2024 - Elsevier
T cells are adaptive immune cells essential in pathogenic response, cancer, and
autoimmune disorders. During the integration of biomaterials with host tissue, T cells modify …

Age-related bone diseases: Role of inflammaging

J Bi, C Zhang, C Lu, C Mo, J Zeng, M Yao, B Jia… - Journal of …, 2024 - Elsevier
Bone aging is characterized by an imbalance in the physiological and pathological
processes of osteogenesis, osteoclastogenesis, adipogenesis, and chondrogenesis …

From bench to bedside-is there a role of IL-17 drugs in rheumatoid arthritis?

S Byravan, H Samarasinghe, JSJ Yuan… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction IL-17 has been described as a pro-inflammatory cytokine that is relevant in the
seronegative spondylarthritides with IL-17 targeted therapies being licensed for their …

Mechanism of action of gut microbiota and probiotic Lactobacillus rhamnosus GG on skeletal remodeling in mice

AM Tyagi - Endocrinology, Diabetes & Metabolism, 2024 - Wiley Online Library
Introduction Gut microbiota (GM) is the collection of small organisms such as bacteria, fungi,
bacteriophages and protozoans living in the intestine in symbiotics relation within their host …

The role of MIF in periodontitis: A potential pathogenic driver, biomarker, and therapeutic target

T Fang, L Liu, D Song, D Huang - Oral Diseases, 2024 - Wiley Online Library
Objective Periodontitis is an inflammatory disease that involves an imbalance in the oral
microbiota, activation of inflammatory and immune responses, and alveolar bone …