Major depressive disorder: hypothesis, mechanism, prevention and treatment

L Cui, S Li, S Wang, X Wu, Y Liu, W Yu… - … and Targeted Therapy, 2024 - nature.com
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

Failure of scabies treatment: a systematic review and meta-analysis

L Mbuagbaw, B Sadeghirad, RL Morgan… - British Journal of …, 2024 - academic.oup.com
Background Treatment failure is considered to be an important factor in relation to the
increase in scabies incidence over the last decade. However, the regional and temporal …

Effects of DMT on mental health outcomes in healthy volunteers

C Timmermann, RJ Zeifman, D Erritzoe, DJ Nutt… - Scientific Reports, 2024 - nature.com
Psilocybin, a serotonergic psychedelic, is being increasingly researched in clinical studies
for the treatment of psychiatric disorders. The relatively lengthy duration of oral psilocybin's …

Modulating the catalytic activities of nanozymes for molecular sensing

I Zare, D Choi, J Zhang, MT Yaraki, A Ghaee, SZ Nasab… - Nano Today, 2024 - Elsevier
Nanomaterials as artificial enzymes (nanozymes) have aroused extensive research interest
owing to their highly stable, long storage period, and low-cost alternatives to enzymes …

Regional disparities, age-related changes and sex-related differences in knee osteoarthritis

J Di, J Bai, J Zhang, J Chen, Y Hao, J Bai… - BMC Musculoskeletal …, 2024 - Springer
Background The objective of the study is to analyse the regions, age and sex differences in
the incidence of knee osteoarthritis (KOA). Methods Data were extracted from the global …

Real-life Assessment of BioFire FilmArray Pneumonia Panel in Adults Hospitalized With Respiratory Illness

AR Falsey, AR Branche, DP Croft… - The Journal of …, 2024 - academic.oup.com
Background Inability to identify the microbial etiology of lower respiratory tract infection leads
to unnecessary antibiotic use. We evaluated the utility of the BioFire FilmArray Pneumonia …

Impact of stress on brain morphology: insights into structural biomarkers of stress-related disorders

R Andero, M Cano, I Marin-Blasco… - Current …, 2024 - ingentaconnect.com
Exposure to acute and chronic stress has a broad range of structural effects on the brain.
The brain areas commonly targeted in the stress response models include the …

Artificial intelligence in advancing occupational health and safety: an encapsulation of developments

IA Shah, SD Mishra - Journal of Occupational Health, 2024 - academic.oup.com
Objectives: In an era characterized by dynamic technological advancements, the well-being
of the workforce remains a cornerstone of progress and sustainability. The evolving …

Fisetin suppresses ferroptosis through Nrf2 and attenuates intervertebral disc degeneration in rats

C Li, Y Zhang, Y Deng, Y Chen, C Wu, X Zhao… - European Journal of …, 2024 - Elsevier
Low back pain, primarily caused by intervertebral disc degeneration (IVDD), lacks effective
pharmacological treatments. Oxidative stress has been identified as a significant contributor …

Cardiovascular disorders and falls among older adults: a systematic review and meta-analysis

R Bourke, P Doody, S Pérez, D Moloney… - The Journals of …, 2024 - academic.oup.com
Background Falls are a common cause of injury, hospitalization, functional decline, and
residential care admission among older adults. Cardiovascular disorders are recognized …