Gut microbiota induced epigenetic modifications in the non‐alcoholic fatty liver disease pathogenesis

R Tang, R Liu, H Zha, Y Cheng… - Engineering in Life …, 2024 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) represents a growing global health concern that
can lead to liver disease and cancer. It is characterized by an excessive accumulation of fat …

[HTML][HTML] Double Trouble: How Microbiome Dysbiosis and Mitochondrial Dysfunction Drive Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis

W Bahitham, S Alghamdi, I Omer, A Alsudais, I Hakeem… - Biomedicines, 2024 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are
closely related liver conditions that have become more prevalent globally. This review …

Characteristics of microbiome-derived metabolomics according to the progression of alcoholic liver disease

R Ganesan, H Gupta, JJ Jeong, SP Sharma… - Hepatology …, 2024 - Springer
Background and aim The prevalence and severity of alcoholic liver disease (ALD) are
increasing. The incidence of alcohol-related cirrhosis has risen up to 2.5%. This study aimed …

[HTML][HTML] Efficacy of endophytic bacteria as promising inducers for enhancing the immune responses in tomato plants and managing Rhizoctonia root-rot disease

MM Abbas, WH Ismael, AY Mahfouz, GE Daigham… - Scientific Reports, 2024 - nature.com
Around the world, a variety of crops, including tomatoes, suffer serious economic losses due
to the Rhizoctonia root-rot disease. Herein, Bacillus velezensis, Bacillus megaterium, and …

[HTML][HTML] Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases

SG Rodrigues, S van der Merwe, A Krag… - Seminars in immunology, 2024 - Elsevier
“A healthy liver stands on a healthy gut” with the gut and its barriers representing the roots
that fuel the liver and expose it to an amazing diverse mixture of gut-derived material/agents …

[HTML][HTML] Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications …

KR LeFort, W Rungratanawanich, BJ Song - Cellular and Molecular Life …, 2024 - Springer
This review provides an update on recent findings from basic, translational, and clinical
studies on the molecular mechanisms of mitochondrial dysfunction and apoptosis of …

[HTML][HTML] Metformin exerts anti-liver fibrosis effect based on the regulation of gut microbiota homeostasis and multi-target synergy

L Kong, J Ma, L Dong, C Zhu, J Zhang, J Li - Heliyon, 2024 - cell.com
Liver fibrosis can progress to cirrhosis if left untreated. Therefore, identifying effective
antifibrotic drugs is crucial. This study aimed to investigate the role and potential mechanism …

[HTML][HTML] Causal Relationship Between Gut Microbiota and Liver Cirrhosis: 16S rRNA Sequencing and Mendelian Randomization Analyses

M Yuan, X Hu, L Yao, P Chen, Z Wang… - Journal of Clinical …, 2024 - ncbi.nlm.nih.gov
Methods We first assessed the differences in the composition of the bacterial community
between CCl4-induced liver cirrhosis and control mice using 16S rRNA sequencing. We …

[HTML][HTML] Liver cirrhosis and complications from the perspective of dysbiosis

G Nie, H Zhang, D Xie, J Yan, X Li - Frontiers in Medicine, 2024 - frontiersin.org
The gut-liver axis refers to the intimate relationship and rigorous interaction between the gut
and the liver. The intestinal barrier's integrity is critical for maintaining liver homeostasis. The …

[HTML][HTML] Gut microbial diversity and functional characterization in people with alcohol use disorder: A case-control study

D Piacentino, C Vizioli, JJ Barb, S Grant-Beurmann… - Plos one, 2024 - journals.plos.org
Individuals with Alcohol Use Disorder (AUD) typically have comorbid chronic health
conditions, including anxiety and depression disorders, increased sleep disruption, and …