Metabolic changes contribute to cancer initiation and progression through effects on cancer
cells, the tumor microenvironment and whole-body metabolism. Alterations in serine …

Lung cancer is a highly fatal disease that poses a significant global health burden. The
absence of characteristic clinical symptoms frequently results in the diagnosis of most …

NKG2D is an activating receptor expressed by all human NK cells and CD8 T cells.
Harnessing the NKG2D/NKG2D ligand axis has emerged as a viable avenue for cancer …

Due to its insidious nature, lung cancer remains a leading cause of cancer-related deaths
worldwide. Therefore, there is an urgent need to identify sensitive/specific biomarkers for …

Kidney disease is a devastating condition affecting millions of people worldwide, where over
100,000 patients in the United States alone remain waiting for a lifesaving organ transplant …

Enzymatic molecular in situ self-assembly (E-MISA) that enables the synthesis of high-order
nanostructures from synthetic small molecules inside a living subject has emerged as a …

Background Glycine dehydrogenase (GLDC) plays an important role in the initiation and
proliferation of several human cancers. In this study, we aimed to detect the methylation …

Lung cancer remains the leading cause of cancer mortality. Screening guidelines have been
implemented in the past decade to aid in earlier detection of at-risk groups. Nevertheless …

Autophagy is a globally conserved cellular activity that plays a critical role in maintaining
cellular homeostasis through the breakdown and recycling of cellular constituents. In recent …

Mitochondrial one-carbon metabolism provides carbon units to several pathways, including
nucleic acid synthesis, mitochondrial metabolism, amino acid metabolism, and methylation …