Treating depression in patients with borderline personality disorder: clinical clues on the use of antidepressants

C Tomasetti, G Autullo, A Ballerini… - Annals of General …, 2024 - Springer
Personality disorders (PD) are described as enduring patterns of markedly deviant and
pervasive inner experiences and behaviors, with onset in adolescence, which lead to severe …

DISC1 and reelin interact to alter cognition, inhibition, and neurogenesis in a novel mouse model of schizophrenia

HL Mahoney, CA Bloom, HS Justin… - Frontiers in Cellular …, 2024 - frontiersin.org
The etiology of schizophrenia (SCZ) is multifactorial, and depending on a host of genetic
and environmental factors. Two putative SCZ susceptibility genes, Disrupted-in …

[HTML][HTML] Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus

CM Mathey, C Maj, N Eriksson, K Krebs… - Journal of Allergy and …, 2024 - Elsevier
Background Angioedema is a rare but potentially life-threatening adverse drug reaction in
patients receiving angiotensin-converting enzyme inhibitors (ACEis). Research suggests …

Systemic inflammatory biomarkers in Schizophrenia are changed by ECT administration and related to the treatment efficacy

Y Wang, G Wang, M Gong, Y Yang, Y Ling, X Fang… - BMC psychiatry, 2024 - Springer
Immune inflammation has long been implicated in the pathogenesis of schizophrenia.
Despite as a rapid and effective physical therapy, the role of immune inflammation in …

[HTML][HTML] Dissecting Schizophrenia Biology Using Pleiotropy with Cognitive Genomics

U Bhattacharyya, J John, T Lencz, M Lam - medRxiv, 2024 - ncbi.nlm.nih.gov
Given the increasingly large number of loci discovered by psychiatric GWAS, specification of
the key biological pathways underlying these loci has become a priority for the field. We …

Epigenetics in neurobehavioral disease

S Løkhammer - Epigenetics in Human Disease, 2024 - Elsevier
In recent years, the rapid development of new technologies and bioinformatic tools has
given increasingly more sophisticated ways to investigate the epigenome. These …

Genetic modifiers of somatic expansion and clinical phenotypes in Huntington's disease reveal shared and tissue-specific effects

Genetic Modifiers of Huntington's Disease (GeM-HD) … - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD), due to expansion of a CAG repeat in HTT, is representative of a
growing number of disorders involving somatically unstable short tandem repeats. We find …