[HTML][HTML] Molecular Organization and Regulation of the Mammalian Synapse by the Post-Translational Modification SUMOylation
Neurotransmission occurs within highly specialized compartments forming the active
synapse where the complex organization and dynamics of the interactions are tightly …
synapse where the complex organization and dynamics of the interactions are tightly …
Autism spectrum disorder: pathogenesis, biomarker, and intervention therapy
H Zhuang, Z Liang, G Ma, A Qureshi, X Ran… - MedComm, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) has become a common neurodevelopmental disorder. The
heterogeneity of ASD poses great challenges for its research and clinical translation. On the …
heterogeneity of ASD poses great challenges for its research and clinical translation. On the …
[HTML][HTML] Curation of causal interactions mediated by genes associated with autism accelerates the understanding of gene-phenotype relationships underlying …
Autism spectrum disorder (ASD) comprises a large group of neurodevelopmental conditions
featuring, over a wide range of severity and combinations, a core set of manifestations …
featuring, over a wide range of severity and combinations, a core set of manifestations …
[PDF][PDF] Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity
Y Miyazaki, T Otsuka, Y Yamagata, T Endo, M Sanbo… - Cell Reports, 2024 - cell.com
Neurodevelopmental disorders, such as intellectual disability (ID), epilepsy, and autism,
involve altered synaptic transmission and plasticity. Functional characterization of their …
involve altered synaptic transmission and plasticity. Functional characterization of their …
Increased number of excitatory synapsis and decreased number of inhibitory synapsis in the prefrontal cortex in autism
G Vakilzadeh, BC Maseko, TD Bartely… - Cerebral …, 2024 - academic.oup.com
Previous studies in autism spectrum disorder demonstrated an increased number of
excitatory pyramidal cells and a decreased number of inhibitory parvalbumin+ chandelier …
excitatory pyramidal cells and a decreased number of inhibitory parvalbumin+ chandelier …
[HTML][HTML] FLNA regulates neuronal maturation by modulating RAC1-Cofilin activity in the developing cortex
A Falace, L Corbieres, C Palminha, FC Guarnieri… - Neurobiology of …, 2024 - Elsevier
Periventricular nodular heterotopia (PNH), the most common brain malformation diagnosed
in adulthood, is characterized by the presence of neuronal nodules along the ventricular …
in adulthood, is characterized by the presence of neuronal nodules along the ventricular …
Gonadal hormones impart male-biased behavioral vulnerabilities to immune activation via microglial mitochondrial function
EA Bordt, HA Moya, YC Jo, CT Ravichandran… - Brain, Behavior, and …, 2024 - Elsevier
There is a strong male bias in the prevalence of many neurodevelopmental disorders such
as autism spectrum disorder. However, the mechanisms underlying this sex bias remain …
as autism spectrum disorder. However, the mechanisms underlying this sex bias remain …
Running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of CUS-induced depression model mice
Y Li, Y Luo, P Zhu, X Liang, J Li, X Dou, L Liu… - Pharmacology …, 2024 - Elsevier
Although the antidepressant effects of running exercise have been widely reported, further
research is still needed to determine the structural bases for these effects. Astrocyte …
research is still needed to determine the structural bases for these effects. Astrocyte …
[HTML][HTML] iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity
L Rylaarsdam, J Rakotomamonjy, E Pope… - Nature …, 2024 - nature.com
PACS1 syndrome is a neurodevelopmental disorder characterized by intellectual disability
and distinct craniofacial abnormalities resulting from a de novo p. R203W variant in …
and distinct craniofacial abnormalities resulting from a de novo p. R203W variant in …
Memristors Constructed by CsPbIBr2 Inorganic Halide Perovskite for Artificial Synapse and Logic Operation
Y Long, X Chen, X Pan, J Duan, X Li… - physica status solidi …, 2024 - Wiley Online Library
Neuromorphic devices are one of the promising electronic devices that are implementing
artificial neural networks and substituting for traditional semiconductor devices in recent …
artificial neural networks and substituting for traditional semiconductor devices in recent …