Parkinson's disease and photobiomodulation: Potential for treatment
B Bicknell, A Liebert, G Herkes - Journal of Personalized Medicine, 2024 - mdpi.com
Parkinson's disease is the second most common neurodegenerative disease and is
increasing in incidence. The combination of motor and non-motor symptoms makes this a …
increasing in incidence. The combination of motor and non-motor symptoms makes this a …
Pathogenesis of DJ-1/PARK7-mediated Parkinson's disease
LD Skou, SK Johansen, J Okarmus, M Meyer - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a common movement disorder associated with the degeneration
of dopaminergic neurons in the substantia nigra pars compacta. Mutations in the PD …
of dopaminergic neurons in the substantia nigra pars compacta. Mutations in the PD …
Ubiquitin Carboxyl-Terminal Hydrolase L1 and Its Role in Parkinson's Disease
O Buneeva, A Medvedev - International Journal of Molecular Sciences, 2024 - mdpi.com
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1), also known as Parkinson's disease
protein 5, is a highly expressed protein in the brain. It plays an important role in the ubiquitin …
protein 5, is a highly expressed protein in the brain. It plays an important role in the ubiquitin …
Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson's Disease
Parkinson's disease (PD) is the second most prevalent neurodegenerative movement
disorder worldwide, which is primarily characterized by motor impairments. Even though …
disorder worldwide, which is primarily characterized by motor impairments. Even though …
Empagliflozin repurposing in Parkinson's disease; modulation of oxidative stress, neuroinflammation, AMPK/SIRT-1/PGC-1α, and wnt/β-catenin pathways
Parkinson's disease is a neuroprogressive disorder characterized by loss of dopaminergic
neurons in substantia nigra pars compacta. Empagliflozin (EMPA), a SGLT-2 inhibitor, is an …
neurons in substantia nigra pars compacta. Empagliflozin (EMPA), a SGLT-2 inhibitor, is an …
Initial Molecular Mechanisms of the Pathogenesis of Parkinson's Disease in a Mouse Neurotoxic Model of the Earliest Preclinical Stage of This Disease
A Kolacheva, E Pavlova, A Bannikova… - International Journal of …, 2024 - mdpi.com
Studying the initial molecular mechanisms of the pathogenesis of Parkinson's disease (PD),
primarily in the nigrostriatal dopaminergic system, is one of the priorities in neurology. Of …
primarily in the nigrostriatal dopaminergic system, is one of the priorities in neurology. Of …
Parkinson's disease and Parkinsonism syndromes: Evaluating iron deposition in the putamen using magnetic susceptibility MRI techniques-A systematic review and …
S Mohammadi, S Ghaderi - Heliyon, 2024 - cell.com
Magnetic resonance imaging (MRI) techniques, such as quantitative susceptibility mapping
(QSM) and susceptibility-weighted imaging (SWI), can detect iron deposition in the brain …
(QSM) and susceptibility-weighted imaging (SWI), can detect iron deposition in the brain …
Aging accelerates locomotor decline in PINK1 knockout rats in association with decreased nigral, but not striatal, dopamine and tyrosine hydroxylase expression
I Soto, R McManus, W Navarrete, EA Kasanga… - Experimental …, 2024 - Elsevier
Parkinson's disease (PD) rodent models provide insight into the relationship between
nigrostriatal dopamine (DA) signaling and locomotor function. Although toxin-based rat …
nigrostriatal dopamine (DA) signaling and locomotor function. Although toxin-based rat …
Prevention of Parkinson's disease: from risk factors to early interventions
Parkinson's disease (PD) is a debilitating neurological disorder characterized by
progressively worsening motor dysfunction. Currently, available therapies merely alleviate …
progressively worsening motor dysfunction. Currently, available therapies merely alleviate …
Buty and the beast: the complex role of butyrate in Parkinson's disease
Parkinson's disease (PD) is a complex neurodegenerative disease which is often associated
with gastrointestinal (GI) dysfunction. The GI tract is home to a wide range of …
with gastrointestinal (GI) dysfunction. The GI tract is home to a wide range of …