Background Disorders affecting the nervous system are diverse and include
neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions …

Objective Vascular neurosurgery has developed significantly in Nigeria, but its burden and
challenges remain unclear. This study systematically reviewed vascular neurosurgical …

BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Neuroinflammation has emerged as a major concern in ischemic stroke therapy because it
exacebates neurological dysfunction and suppresses neurological recovery after …

Butylphthalide is one of the first-line drugs for ischemic stroke therapy, while no biosynthetic
enzyme for butylphthalide has been reported. Here, we present a haplotype-resolved …

Stroke results in local neural disconnection and brain-wide neuronal network dysfunction
leading to neurological deficits. Beyond the hyper-acute phase of ischaemic stroke, there is …

The gut microbiome interacts with the brain bidirectionally through the microbiome-gutbrain
axis, which plays a key role in regulating various nervous system pathophysiological …

OBJECTIVE Nontraumatic intracerebral hemorrhage (ICH) is a potentially devastating
cerebrovascular disorder. Several randomized trials have assessed interventions to improve …

Background In this study we correlated changes of risk factors for cardiovascular diseases
with trends of age standardized mortality rates and burden for aortic aneurysms and …

There are few effective and safe neuroprotective agents for the treatment of ischemic stroke
currently. Caffeic acid is a phenolic acid that widely exists in a number of plant species …