Cardiovascular toxicities following the use of tyrosine kinase inhibitors in Hepatocellular Cancer Patients: A Retrospective, Pharmacovigilance Study
X Lai, Q Wan, S Jiao, X Sun, J Hu… - Expert Opinion on Drug …, 2024 - Taylor & Francis
ABSTRACT Background Cardiac adverse events (AEs) are common in tyrosine kinase
inhibitors (TKIs). This study explored the cardiac AEs of TKIs through the Food and Drug …
inhibitors (TKIs). This study explored the cardiac AEs of TKIs through the Food and Drug …
Advancements in Immunotherapeutic Treatments for Hepatocellular Carcinoma: Potential of Combination Therapies
Y Zarlashat, H Mushtaq, L Pham, W Abbas… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and a significant global
health burden, with increasing incidence rates and limited treatment options …
health burden, with increasing incidence rates and limited treatment options …
Long-term trends in incidence, mortality and burden of liver cancer due to specific etiologies in Hubei Province
H Liu, J Li, S Zhu, X Zhang, F Zhang, X Zhang… - Scientific Reports, 2024 - nature.com
Liver cancer, a chronic non-communicable disease, represents a serious public health
problem. Long-term trends in the burden of liver cancer disease are heterogeneous across …
problem. Long-term trends in the burden of liver cancer disease are heterogeneous across …
Matrin-3 acts as a potential biomarker and promotes hepatocellular carcinoma progression by interacting with cell cycle-regulating genes
H He, M Jamal, X Zeng, Y Lei, D Xiao, Z Wei, C Zhang… - Cell Cycle, 2024 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality
worldwide. The oncogenic role of Matrin-3 (MATR3), an a nuclear matrix protein, in HCC …
worldwide. The oncogenic role of Matrin-3 (MATR3), an a nuclear matrix protein, in HCC …
Focal adhesion kinase confers lenvatinib resistance in hepatocellular carcinoma via the regulation of lysine‐deficient kinase 1
W Hou, SA Gad, X Ding, A Dhanarajan… - Molecular …, 2024 - Wiley Online Library
Lenvatinib is a clinically effective multikinase inhibitor approved for first‐line therapy of
advanced hepatocellular carcinoma (HCC). Although resistance against lenvatinib often …
advanced hepatocellular carcinoma (HCC). Although resistance against lenvatinib often …
Boron-Containing Mesoporous Silica Nanoparticles with Effective Delivery and Targeting of Liver Cancer Cells for Boron Neutron Capture Therapy
H Tang, Z Wang, H Hao, W Luo, J Yang… - … Applied Materials & …, 2024 - ACS Publications
Nanocarriers have been researched comprehensively for the development of novel boron-
containing agents in boron neutron capture therapy (BNCT). We designed and synthesized …
containing agents in boron neutron capture therapy (BNCT). We designed and synthesized …
Autophagy inhibition potentiates energy restriction‐induced cell death in hepatocellular carcinoma cells
SM Elgendy, DM Zaher, NH Sarg, NN Abu Jayab… - IUBMB …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) significantly contributes to cancer‐related mortality due to
the limited response of HCC to current anticancer therapies, thereby necessitating more …
the limited response of HCC to current anticancer therapies, thereby necessitating more …
[HTML][HTML] Investigation of prunetrin induced G2/M cell cycle arrest and apoptosis via Akt/mTOR/MAPK pathways in hepatocellular carcinoma cells
A Abusaliya, PB Bhosale, HH Kim, MY Park… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) stands as a leading cause of mortality, and despite recent
advancements in the overall survival rates, the prognosis remains dismal. Prunetin 4-O …
advancements in the overall survival rates, the prognosis remains dismal. Prunetin 4-O …
The State of Systematic Therapies in Clinic for Hepatobiliary Cancers
W Chen, Z Hu, G Li, L Zhang, T Li - Journal of Hepatocellular …, 2024 - Taylor & Francis
Hepatobiliary cancer (HBC) includes hepatocellular carcinoma and biliary tract carcinoma
(cholangiocarcinoma and gallbladder carcinoma), and its morbidity and mortality are …
(cholangiocarcinoma and gallbladder carcinoma), and its morbidity and mortality are …
Effects of mesenchymal stem cells versus curcumin on sonic hedgehog signaling in experimental model of Hepatocellular Carcinoma
MS Abdel-Tawab, H Fouad, AY Sedeak… - Molecular Biology …, 2024 - Springer
Abstract Background Sonic Hedgehog (SHH) is a fundamental signaling pathway that
controls tissue reconstruction, stem cell biology, and differentiation and has a role in gut …
controls tissue reconstruction, stem cell biology, and differentiation and has a role in gut …