[HTML][HTML] Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: in vitro and in vivo studies

M Yasser, EE El Naggar, N Elfar, MH Teaima… - International Journal of …, 2024 - Elsevier
The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …

Research progress of nano delivery systems for intraocular pressure lowering drugs

X Zhou, D Zhou, X Zhang, L Liao, P Wu, B Chen… - Heliyon, 2024 - cell.com
Glaucoma is a chronic ocular disease characterized by optic atrophy and visual field defect.
The main risk factor for glaucoma onset and progression is elevated intraocular pressure …

Formulation and in Vitro-Ex vivo evaluation of cannabidiol and Cannabidiol-Valine-Hemisuccinate loaded Lipid-Based nanoformulations for ocular applications

AAA Youssef, MH Abdelrahman, MM Geweda… - International Journal of …, 2024 - Elsevier
The goal of this investigation is to develop stable ophthalmic nanoformulations containing
cannabidiol (CBD) and its analog cannabidiol-valine-hemisuccinate (CBD-VHS) for …

[HTML][HTML] Antimicrobial Nanoemulsion: A futuristic approach in antibacterial drug delivery system

SB JP, P Sahu, R Vinode, A Patel, MN Alomary… - Journal of Saudi …, 2024 - Elsevier
Complex, kinetically stable emulsions with an average droplet size of 50–100 nm and a
mean droplet diameter of 50–1000 nm is known as nanoemulsions. They are often referred …

Micro and nanoemulsions in colorectal cancer

B Basu, K Garala, A Dutta, R Joshi, BG Prajapati… - Colorectal Cancer, 2024 - Elsevier
Abstract Nano/microemulsions (NE/MEs) are a promising drug delivery system (DDS) for
cancer therapy because they target tumor cells specifically while avoiding multidrug …

Prednisolone loaded-cationic nanoemulsion formulation for uveitis management

MA Attia, NE Eleraky, K Abdelazeem… - Journal of Drug Delivery …, 2024 - Elsevier
Uveitis is a sight-threatening complication that continues to be a major contributor to
blindness. The etiology of uveitis mostly depends on inflammatory activities. The mainstay of …

Development of brimonidine niosomes laden contact lenses for extended release and promising delivery system in glaucoma treatment

S Tripathi, KS Yadav - DARU Journal of Pharmaceutical Sciences, 2024 - Springer
Background Increased intraocular pressure is a common symptom of glaucoma. In severe
circumstances, it may result in loss of eyesight. Glaucoma treatment is difficult due to ocular …

Novel functions of o-cymen-5-ol nanoemulsion in reversing colistin resistance in multidrug-resistant Klebsiella pneumoniae infections

Q Sheng, X Wang, Z Hou, B Liu, M Jiang, M Ren… - Biochemical …, 2024 - Elsevier
Multidrug resistance (MDR) Klebsiella pneumoniae (K. pneumoniae) is a major emerging
threat to human health, and leads to very high mortality rate. The effectiveness of colistin, the …

Limonene-Enriched Ultra-Structural Cubosomes to Augment Ocular Delivery of a Poorly Water Soluble Anti-Fungal Drug: Fabrication, Characterization, Statistical …

AA Nemr, S Ahmed, IM Adel - Journal of Drug Delivery Science and …, 2024 - Elsevier
The target of this investigation was to obtain the composition of the optimized Fenticonazole
nitrate (FCN)-loaded cubosomal formula that can prolong precorneal retention, increase …

Suspensions of antibiotics in self-emulsifying oils as a novel approach to formulate eye drops with substances which undergo hydrolysis in aqueous environment

K Krzeminska, M Sznitowska, M Wroblewska… - Drug Delivery, 2024 - Taylor & Francis
The aim of this study was to develop eye-drops with cefuroxime (CEF) sodium or
vancomycin (VAN) hydrochloride, antibiotics that are instable in water. Anhydrous self …