Competition among adult brain cells has not been extensively researched. To investigate
whether healthy glia can outcompete diseased human glia in the adult forebrain, we …

The aggregation of proteins into amyloid-like fibrils is seen in many neurodegenerative
diseases. Recent years have seen much progress in our understanding of these misfolded …

Huntington's disease (HD) is a neurodegenerative genetic disorder characterized by a
mutation in the huntingtin (HTT) gene, resulting in the production of a mutant huntingtin …

Huntington's disease (HD) is a neurodegenerative disorder caused by expansion of a CAG
trinucleotide repeat in the Huntingtin (HTT) gene, encoding a homopolymeric polyglutamine …

Huntington's disease (HD) is a neurodegenerative disorder involving psychiatric, cognitive
and motor deficits, as well as peripheral symptoms, including gastrointestinal dysfunction …

Protein aggregates, formed from the assembly of aberrant, misfolded proteins, are a
hallmark of neurodegenerative diseases. Disease-associated aggregates such as mutant …

Pathogenic huntingtin exon‐1 protein (httex1), characterized by an expanded polyglutamine
tract located between the N‐terminal amphiphilic region and a C‐terminal polyproline‐rich …

The Huntington's disease mutation is a CAG repeat expansion in the huntingtin gene that
results in an expanded polyglutamine tract in the huntingtin protein. The CAG repeat is …

Huntington's disease (HD) arises from the abnormal expansion of CAG repeats in the
huntingtin gene (HTT), resulting in the production of the mutant huntingtin protein (mHTT) …

Extracellular vesicles are shed by every cell type and can be found in any biofluid. They
contain different molecules that can be utilized as biomarkers, including several RNA …