Point‐Of‐Care Ultra‐Portable Single‐Molecule Bioassays for One‐Health

E Macchia, F Torricelli, M Caputo, L Sarcina… - Advanced …, 2024 - Wiley Online Library
Screening asymptomatic organisms (humans, animals, plants) with a high‐diagnostic
accuracy using point‐of‐care‐testing (POCT) technologies, though still visionary holds great …

[HTML][HTML] Integrating a microRNA signature as a liquid biopsy-based tool for the early diagnosis and prediction of potential therapeutic targets in pancreatic cancer

W Shi, T Wartmann, S Accuffi, S Al-Madhi… - British Journal of …, 2024 - nature.com
Introduction Pancreatic cancer is a highly aggressive cancer, and early diagnosis
significantly improves patient prognosis due to the early implementation of curative-intent …

[HTML][HTML] Optical nanomaterial-based detection of biomarkers in liquid biopsy

YJ Kim, WY Rho, S Park, BH Jun - Journal of Hematology & Oncology, 2024 - Springer
Liquid biopsy, which is a minimally invasive procedure as an alternative to tissue biopsy,
has been introduced as a new diagnostic/prognostic measure. By screening disease-related …

Accurate non-invasive grading of nonfunctional pancreatic neuroendocrine tumors with a CT derived radiomics signature

AA Javed, Z Zhu, B Kinny-Köster, JR Habib… - Diagnostic and …, 2024 - Elsevier
Purpose The purpose of this study was to develop a radiomics-signature using computed
tomography (CT) data for the preoperative prediction of grade of nonfunctional pancreatic …

Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer

R Ben-Ami, QL Wang, J Zhang, JG Supplee… - Gut, 2024 - gut.bmj.com
Objective Pancreatic ductal adenocarcinoma (PDAC) is commonly diagnosed at an
advanced stage. Liquid biopsy approaches may facilitate detection of early stage PDAC …

Ultrasensitive and High‐Resolution Protein Spatially Decoding Framework for Tumor Extracellular Vesicles

CA Cheng, KC Hou, CW Hsu, LC Chiang - Advanced Science, 2024 - Wiley Online Library
Proteins localized on the surface or within the lumen of tumor‐derived extracellular vesicles
(EVs) play distinct roles in cancer progression. However, quantifying both populations of …

Circulating cell‐free DNA methylation‐based multi‐omics analysis allows early diagnosis of pancreatic ductal adenocarcinoma

G Zhao, R Jiang, Y Shi, S Gao, D Wang, Z Li… - Molecular …, 2024 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a 5‐year
survival rate of 7.2% in China. However, effective approaches for diagnosis of PDAC are …

Omics-based molecular classifications empowering in precision oncology

Z Zhou, T Lin, S Chen, G Zhang, Y Xu, H Zou, A Zhou… - Cellular Oncology, 2024 - Springer
Background In the past decades, cancer enigmatical heterogeneity at distinct expression
levels could interpret disparities in therapeutic response and prognosis. It built hindrances to …

[HTML][HTML] Ultra-short cell-free DNA fragments enhance cancer early detection in a multi-analyte blood test combining mutation, protein and fragmentomics

F Wang, X Li, M Li, W Liu, L Lu, Y Li, X Chen… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives Cancer morbidity and mortality can be reduced if the cancer is detected early.
Cell-free DNA (cfDNA) fragmentomics emerged as a novel epigenetic biomarker for early …

Strategic approaches in oral squamous cell carcinoma diagnostics using liquid biopsy

DF Kinane, J Gabert, G Xynopoulos… - Periodontology …, 2024 - Wiley Online Library
Liquid biopsy is a noninvasive diagnostic technique used for monitoring cancer utilizing
specific genetic biomarkers present in bodily fluids, such as blood, saliva, or urine. These …