Applications and prospects of microneedles in tumor drug delivery

Q Zhang, X Liu, J He - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
As drug delivery devices, microneedles are used widely in the local administration of various
drugs. Such drug-loaded microneedles are minimally invasive, almost painless, and have …

Microneedles' Device: Design, Fabrication, and Applications

C Oliveira, JA Teixeira, N Oliveira, S Ferreira… - Macromol, 2024 - mdpi.com
The delivery of therapeutical molecules through the skin, particularly to its deeper layers, is
impaired due to the stratum corneum layer, which acts as a barrier to foreign substances …

Rapid dissolution microneedle based on polyvinyl alcohol/chitosan for local oral anesthesia

Q Li, X Yu, X Zheng, J Yang, J Hui, D Fan - International Journal of …, 2024 - Elsevier
At present, the main clinical methods of oral local anesthesia are direct injection of
anesthetic and surface ointment. However, the pain and fear caused by the injection, the …

[HTML][HTML] Machine Learning Assists in the Design and Application of Microneedles

W He, S Kong, R Lin, Y Xie, S Zheng, Z Yin, X Huang… - Biomimetics, 2024 - mdpi.com
Microneedles (MNs), characterized by their micron-sized sharp tips, can painlessly
penetrate the skin and have shown significant potential in disease treatment and …

Stimuli-responsive microneedles for drug delivery

F Hassan-Aghaei, MM Mohebi - … and Applications of Microneedles in Drug …, 2024 - Elsevier
Traditional methods of drug administration, such as oral and injection routes, have
limitations due to factors such as first-pass metabolism and invasiveness. Microneedles …

Au-NPs Functionalizaed Microneedles as Intelligent Components for Portable Devices

S Coppola, V Vespini, A Palma… - … on Metrology for …, 2024 - ieeexplore.ieee.org
Nowadays the direct healthcare cost represent an enormous part of the government welfare
system and it is still increasing worldwide. The development of minimally invasive devices …

Microneedles Patch: Design, Fabrication and Applications

C Oliveira, JA Teixeira, N Oliveira, S Ferreira… - 2024 - preprints.org
The delivery of therapeutical molecules through the skin, particularly to its deeper layers is
impaired due to the stratum corneum layer, which acts as barrier to foreign substances …