[HTML][HTML] Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies

MF Rai, KH Collins, A Lang, T Maerz, J Geurts… - Osteoarthritis and …, 2024 - Elsevier
Objective Osteoarthritis (OA) is a complex disease involving contributions from both local
joint tissues and systemic sources. Patient characteristics, encompassing sociodemographic …

Epigenetic Aging and Musculoskeletal Outcomes in a Cohort of Women Living With HIV

S Shiau, F Zumpano, Z Wang, J Shah… - The Journal of …, 2024 - academic.oup.com
Background The relationship between accelerated epigenetic aging and musculoskeletal
outcomes in women with HIV (WWH) has not been studied. Methods We measured DNA …

Causal impact of DNA methylation on refracture in elderly individuals with osteoporosis–a prospective cohort study

B Wen, Y Zhang, J He, L Tan, G Xiao, Z Wang… - BMC Musculoskeletal …, 2024 - Springer
Background Osteoporotic vertebral compression fractures (OVCF) in the elderly increase
refracture risk post-surgery, leading to higher mortality rates. Genome-wide association …

DMR_Kmeans: Identifying Differentially Methylated Regions Based on k-means Clustering and Read Methylation Haplotype Filtering

X Peng, W Cui, X Kong, Y Huang, J Li - Current Bioinformatics, 2024 - ingentaconnect.com
Introduction: Differentially methylated regions (DMRs), including tissue-specific DMRs and
disease-specific DMRs, can be used in revealing the mechanisms of gene regulation and …

Age-related disease: Bones

JN Farr, A Chandra - Aging, 2024 - Elsevier
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Новые молекулярные аспекты патогенеза остеопороза–перспективы ранней диагностики и лечения

АВ Тюрин, КЭ Ахиярова, БИ Ялаев… - Современная …, 2024 - mrj.ima-press.net
Аннотация Остеопороз (ОП)–широко распространенное заболевание, приводящее к
низкотравматическим переломам и являющееся серьезной медицинской и социальной …