Tumor biomarkers for diagnosis, prognosis and targeted therapy
Y Zhou, L Tao, J Qiu, J Xu, X Yang, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …
tumors during tumorigenesis and progression, have been demonstrated to possess critical …
Molecular mechanisms of aging and anti-aging strategies
Y Li, X Tian, J Luo, T Bao, S Wang, X Wu - Cell Communication and …, 2024 - Springer
Aging is a complex and multifaceted process involving a variety of interrelated molecular
mechanisms and cellular systems. Phenotypically, the biological aging process is …
mechanisms and cellular systems. Phenotypically, the biological aging process is …
Curcumin, its derivatives, and their nanoformulations: Revolutionizing cancer treatment
I Ahmad, S Ahmad, A Ahmad… - Cell Biochemistry …, 2024 - Wiley Online Library
Curcumin is a natural compound derived from turmeric and can target malignant tumor
molecules involved in cancer propagation. It has potent antioxidant activity, but its …
molecules involved in cancer propagation. It has potent antioxidant activity, but its …
Hairpin DNA-Based Nanomaterials for Tumor Targeting and Synergistic Therapy
L Shan, Y Li, Y Ma, Y Yang, J Wang… - International Journal …, 2024 - Taylor & Francis
Background While nanoplatform-based cancer theranostics have been researched and
investigated for many years, enhancing antitumor efficacy and reducing toxic side effects is …
investigated for many years, enhancing antitumor efficacy and reducing toxic side effects is …
Precision Detection of Hepatocellular Carcinoma-Associated Telomerase RNA with SA@ Comb-HCR Nanosystem
Y Chen, H Chen, X Chen, Y Zhang, W Tu, J Mo… - Biosensors and …, 2024 - Elsevier
Accurate intracellular visualization of human telomerase RNA (hTR) is imperative for early
diagnosis and treatment monitoring of hepatocellular carcinoma (HCC). While isothermal …
diagnosis and treatment monitoring of hepatocellular carcinoma (HCC). While isothermal …
A triggered DNA nanomachine with enzyme-free for the rapid detection of telomerase activity in a one-step method
H Pang, Y Peng, R Zhang, Z Gao, X Lai, D Li… - Analytica Chimica …, 2024 - Elsevier
Background Telomerase is considered a biomarker for the early diagnosis and clinical
treatment of cancer. The rapid and sensitive detection of telomerase activity is crucial to …
treatment of cancer. The rapid and sensitive detection of telomerase activity is crucial to …
CRL4DCAF4 E3 ligase-mediated degradation of MEN1 transcriptionally reactivates hTERT to sustain immortalization in colorectal cancer cells
Z Ao, D Xiao, J Wu, J Sun, H Liu - Carcinogenesis, 2024 - academic.oup.com
Telomerase reactivation is implicated in approximately 85% of human cancers, yet its
underlying mechanism remains elusive. In this study, we elucidate that the cullin-RING …
underlying mechanism remains elusive. In this study, we elucidate that the cullin-RING …