[HTML][HTML] The potential toxic effects of estrogen exposure on neural and vascular development in zebrafish
C Lu, Y Lv, X Meng, T Yang, Y Liu, G Kou… - Ecotoxicology and …, 2024 - Elsevier
Estrogens and estrogenic chemicals are endocrine-disrupting chemicals (EDCs). The
potential toxicity of EDCs to humans and aquatic organisms has become increasingly …
potential toxicity of EDCs to humans and aquatic organisms has become increasingly …
Validation of a zebrafish developmental defects assay as a qualified alternative test for its regulatory use following the ICH S5 (R3) guideline
AMJ Weiner, I Irijalba, MP Gallego, I Ibarburu… - Reproductive …, 2024 - Elsevier
Zebrafish is a popular toxicology model and provides an ethically acceptable small-scale
analysis system with the complexity of a complete organism. Our goal is to further validate …
analysis system with the complexity of a complete organism. Our goal is to further validate …
Development Features on the Selection of Animal Models for Teratogenic Testing
S Alves-Pimenta, B Colaço, PA Oliveira… - … Testing: Methods and …, 2024 - Springer
Today, the use of animal models from different species continues to represent a fundamental
step in teratogenic testing, despite the increase in alternative solutions that provide an …
step in teratogenic testing, despite the increase in alternative solutions that provide an …
[HTML][HTML] Biological variability hampers the use of skeletal staining methods in zebrafish embryo developmental toxicity assays
J Hoyberghs, J Ball, M Trznadel, M Beekhuijzen… - Reproductive …, 2024 - Elsevier
Zebrafish embryo assays are used by pharmaceutical and chemical companies as new
approach methodologies (NAMs) in developmental toxicity screening. Despite an overall …
approach methodologies (NAMs) in developmental toxicity screening. Despite an overall …
Comparison of the cytotoxicity and zebrafish embryo toxicity of insect repellent ingredients: p-Menthane-3, 8-diol synthesized by green chemistry from Eucalyptus …
G Özokan, A Bilginer, Z Mızrak, S Işıkoğlu… - Drug and Chemical …, 2024 - Taylor & Francis
Bio-sourced insect repellents are becoming more popular due to their safer applications.
Known for its strong fly-repellent property, Cis, trans-para-menthane-3, 8-diol (PMD) is the …
Known for its strong fly-repellent property, Cis, trans-para-menthane-3, 8-diol (PMD) is the …
[HTML][HTML] Toxicokinetics of a developmental toxicity test in zebrafish embryos and larvae: Relationship with drug exposure in humans and other mammals
T Nawaji, N Mizoguchi, R Adachi, H Teraoka - Current Research in …, 2024 - Elsevier
To study the effects of drugs on embryo/fetal development (EFD), developmental and
reproductive toxicity studies in zebrafish (Danio rerio) embryos is expected to be an …
reproductive toxicity studies in zebrafish (Danio rerio) embryos is expected to be an …
[HTML][HTML] Embriões de peixe-zebra (Danio rerio)
OM Ribeiro, L Félix, SM Monteiro… - Revista de Ciência …, 2024 - rce.casadasciencias.org
A utilização de modelos animais vertebrados na investigação tem sido fundamental para a
compreensão dos processos fisiopatológicos humanos. No entanto, nas últimas duas …
compreensão dos processos fisiopatológicos humanos. No entanto, nas últimas duas …
Advancing the Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) towards a sensitive screening assay
J Hoyberghs - 2024 - repository.uantwerpen.be
Within Europe, new approach methodologies (NAMs) for toxicity assessment of xenobiotics
become very important. Several pharmaceutical,(agro) chemical and cosmetic companies …
become very important. Several pharmaceutical,(agro) chemical and cosmetic companies …