Extracellular vesicles are shed by every cell type and can be found in any biofluid. They
contain different molecules that can be utilized as biomarkers, including several RNA …

Nucleic acid biomarker detection has great importance in the diagnosis of disease, the
monitoring of disease progression and the classification of patients according to treatment …

DNA folding thermodynamics are central to many biological processes and biotechnological
applications involving base-pairing. Current methods for predicting stability from DNA …

DNA mismatches, that is, base pairs different from the canonical AT and CG, are involved in
numerous biological processes and can be a problem for technological applications such as …

Locked nucleic acids (LNA) is a modification to DNA that generally increases the melting
temperature in double strands. The nearest-neighbour (NN) provides one of the best …

Successful cancer treatment continues to elude modern medicine and its arsenal of
therapeutic strategies. Therapy resistance is driven by tumor heterogeneity, complex …

Triple negative breast cancer (TNBC), which lacks the ER, PR and HER-2 expressions is
accounted for the 25% of all breast cancer related deaths in 2019. PIM1 oncogenes were …

We expanded the understandings of photonic crystal hydrogel fabrication and swelling
behavior pertaining to their use as sensing materials. Our hydrogels are comprised of a …

The R package rmelting is an interface to the MELTING 5 program (Le Novère, 2001;
Dumousseau et al., 2012) to compute melting temperatures of nucleic acid duplexes …