[HTML][HTML] Synthetic Methods and Pharmacological Potentials of Triazolothiadiazines: A Review

MS Mostafa, IAM Radini, NMA El-Rahman, RE Khidre - Molecules, 2024 - mdpi.com
This review article examines the synthetic pathways for triazolothiadiazine derivatives, such
as triazolo [3, 4-b] thiadiazines, triazolo [5, 1-b] thiadiazines, and triazolo [4, 3-c] …

In vivo anticancer study of sodium 2‐[(4‐oxidobenzylidene) amino]‐6H‐1, 3, 4‐thiadiazine‐5‐olate against Ehrlich ascites carcinoma via targeting PI3K/mTOR …

YW Rizzk, IM El‐Deen, ME Behery… - Chemical Biology & …, 2024 - Wiley Online Library
Thiadiazine‐based components have gained the attention as they afford significant
intervention for cancer therapy. We aimed at assessing the in vivo antitumor activity of …

Anticancer Drug Discovery By Structure-Based Repositioning Approach

DH Modh, VM Kulkarni - Mini Reviews in Medicinal Chemistry, 2024 - ingentaconnect.com
Despite the tremendous progress that has occurred in recent years in cell biology and
oncology, in chemical, physical and computer sciences, the disease cancer has continued …

Molecular Docking Studies of 3a, 4-dihydro-3H-[1, 3, 2] oxazaphospholo [3, 4-a] Indole-1-oxide derivatives for Anticancer activity

SI Khalivulla, URS Arigala… - Journal of Molecular …, 2024 - pubs.thesciencein.org
This study evaluates eight novel 3a, 4-dihydro-3H-[1, 3, 2] oxazaphospholo [3, 4-a] indole-1-
oxide derivatives (1-8) for their potential as drug candidates. Lipinski's Rule of Five and …