This review analyzes the published evidence regarding maternal factors that influence the
developmental programming of long-term adiposity in humans and animals via the central …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most prevalent pediatric liver
disorder, primarily attributed to dietary shifts in recent years. NAFLD is characterized by the …

Perinatal exposure to a high-fat, high-sugar Western-style diet (WSD) is associated with
altered neural circuitry in the melanocortin system. This association may have an underlying …

Purpose Maternal high-fat diet (HF) programs obesity, metabolic dysfunction-associated
steatotic liver disease (MASLD), hypertriglyceridemia, and hyperglycemia associated with …

Maternal mortality rates are at an all-time high across the world and are set to increase in
subsequent years. Cardiovascular disease is the leading cause of death during pregnancy …

Maternal obesity and over/undernutrition can have a long-lasting impact on offspring health
during critical periods in the first 1000 days of life. Children born to mothers with obesity …

Maternal obesity and hyperglycemia are linked to an elevated risk for obesity, diabetes, and
steatotic liver disease in the adult offspring. To establish and validate a noninvasive …

Pediatric metabolic dysfunction-associated steatotic liver disease (MASLD) is common and
can be seen as early as in utero. A growing body of literature suggests that gestational and …

Background In recent years, pragmatic metformin use in pregnancy has stretched to include
prediabetes, type 2 diabetes, gestational diabetes and (most recently) pre-eclampsia. With …

Metabolic syndrome (MetS) is a cluster of linked and heritable metabolic features like insulin
resistance, obesity, dyslipidemia, hyperglycemia, and hypertension that carries a significant …