[HTML][HTML] The Current and Promising Oral Delivery Methods for Protein-and Peptide-Based Drugs

M Nicze, M Borówka, A Dec, A Niemiec… - International Journal of …, 2024 - mdpi.com
Drugs based on peptides and proteins (PPs) have been widely used in medicine, beginning
with insulin therapy in patients with diabetes mellitus over a century ago. Although the oral …

A green and simple procedure to synthesize dysprosium cerate plate-like nanostructures and their application in the electrochemical sensing of mesalazine

S Zinatloo-Ajabshir, H Mahmoudi-Moghaddam… - Journal of Materials …, 2024 - Springer
This study introduced the synthesizing of plate-like dysprosium cerate (PL-Dy2Ce2O7)
nanoparticles using a simple and fast procedure. The new nanostructure was developed by …

Recent progress on engineered micro/nanomaterials mediated modulation of gut microbiota for treating inflammatory bowel disease

L Kan, Z Zheng, W Fu, Y Ma, W Wang, H Qian… - Journal of Controlled …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is a type of chronic recurrent inflammation disease that
mainly includes Crohn's disease and ulcerative colitis. Currently, the treatments for IBD …

Targeted therapeutic effects of oral magnetically driven pectin nanoparticles containing chlorogenic acid on colon cancer

H Zhu, L Zhang, F Kou, J Zhao, J Lei, J He - Particuology, 2024 - Elsevier
Oral colonic nano-drug delivery system has attracted growing attention in treating colon
cancer for their excellent characteristics. However, the unique and complex structure of the …

[HTML][HTML] Impact of polyethylene glycol and polydopamine coatings on the performance of camptothecin-loaded liposomes for localised treatment of colorectal cancer

AM Maurelli, B Ferreira, S Dias, H Almeida… - Materials …, 2024 - pubs.rsc.org
Management of colorectal cancer (CRC) remains a global healthcare challenge as current
therapies are unable to offer optimal clinical efficacy and meet patient expectations. The oral …

Phospholipids of inhaled liposomes determine the in vivo fate and therapeutic effects of salvianolic acid B on idiopathic pulmonary fibrosis

J Peng, Q Wang, R Sun, K Zhang, Y Chen… - Journal of Controlled …, 2024 - Elsevier
Since phospholipids have an important effect on the size, surface potential and hardness of
liposomes that decide their in vivo fate after inhalation, this research has systematically …

[HTML][HTML] Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended …

S Dohadwala, MT Geib, JA Politch… - … in Reproductive Health, 2024 - frontiersin.org
Monoclonal antibodies (mAbs) are currently being produced for a number of clinical
applications including contraception and the prevention of sexually transmitted infections …

Development of gastric digestion-tolerant plant protein-based nanoparticles: Fabrication, characterization, antioxidant activity, and stability

X Lin, C Zhu, M Chen, PR Gonzalez, X Chen, Z Zhao… - Food …, 2024 - Elsevier
This study aimed to fabricate gastric digestion-tolerant plant protein-based nanoparticles
and to assess their antioxidant activity and stability in relation to their characteristics …

Polyelectrolyte-Doped Block Copolymer-Stabilized Nanocarriers for Continuous Tunable Surface Charge

BK Wilson, H Yang… - ACS Applied Nano …, 2024 - ACS Publications
The surface charge of nanoparticles or nanocarriers (NCs) plays a critical role in the vehicle
function, distribution, and fate in drug delivery applications. Flash NanoPrecipitation (FNP) is …

Applications of polysaccharides in enzyme-triggered oral colon-specific drug delivery systems: A review

T Gong, X Liu, X Wang, Y Lu, X Wang - International Journal of Biological …, 2024 - Elsevier
Enzyme-triggered oral colon-specific drug delivery system (EtOCDDS 1) can withstand the
harsh stomach and small intestine environments, releasing encapsulated drugs selectively …