Artemisinins: Promising drug candidates for the treatment of autoimmune diseases

X Gao, X Lin, Q Wang, J Chen - Medicinal Research Reviews, 2024 - Wiley Online Library
Autoimmune diseases are characterized by the immune system's attack on one's own
tissues which are highly diverse and diseases differ in severity, causing damage in virtually …

[HTML][HTML] Bacteria-derived extracellular vesicles: endogenous roles, therapeutic potentials and their biomimetics for the treatment and prevention of sepsis

CY Effah, X Ding, EK Drokow, X Li, R Tong… - Frontiers in …, 2024 - frontiersin.org
Sepsis is one of the medical conditions with a high mortality rate and lacks specific treatment
despite several years of extensive research. Bacterial extracellular vesicles (bEVs) are …

Limosilactobacillus fermentum HF06‐derived paraprobiotic and postbiotic alleviate intestinal barrier damage and gut microbiota disruption in mice with ulcerative …

C Liu, X Qi, D Li, L Zhao, Q Li, K Mao… - Journal of the …, 2024 - Wiley Online Library
BACKGROUND Paraprobiotics and postbiotics have shown potential in the treatment of
ulcerative colitis (UC). However, their in vivo application is still in its infancy and their …

Plasma extracellular vesicle LncRNA H19 as a potential diagnostic biomarker for inflammatory bowel diseases

R Heydari, S Fayazzadeh, S Shahrokh… - Inflammatory Bowel …, 2024 - academic.oup.com
Background Inflammatory bowel disease (IBD) is a complex gastrointestinal disease with 2
main subtypes of Crohn's disease (CD) and ulcerative colitis (UC), whose diagnosis mainly …

[HTML][HTML] Lactiplantibacillus plantarum HY7718 Improves Intestinal Integrity in a DSS-Induced Ulcerative Colitis Mouse Model by Suppressing Inflammation through …

HJ Kim, HJ Jeon, JY Kim, JJ Shim, JH Lee - International Journal of …, 2024 - mdpi.com
Inflammatory bowel disease (IBD), a chronic condition that causes persistent inflammation in
the digestive system, is closely associated with the intestinal microbiome. Here, we …

[HTML][HTML] Diosmin alleviates ulcerative colitis in mice by increasing Akkermansia muciniphila abundance, improving intestinal barrier function, and modulating the NF …

MB Salem, NM El-Lakkany, SHS El-Din, OA Hammam… - Heliyon, 2024 - cell.com
Ulcerative colitis is a common type of inflammatory bowel disease that affects millions of
individuals around the world. Traditional UC treatment has focused on suppressing immune …

Research progress of interleukin-27 in inflammatory bowel disease

Q Wang, F Chen, Y Peng, X Yi, Y He… - Inflammatory Bowel …, 2024 - academic.oup.com
Inflammatory bowel disease (IBD) can be identified as an inflammatory disorder in the
intestine, being characterized by maladjusted immune responses and chronic inflammation …

Targeting T-cell integrins in autoimmune and inflammatory diseases

AJ Kelly, A Long - Clinical and Experimental Immunology, 2024 - academic.oup.com
The recruitment of T cells to tissues and their retention there are essential processes in the
pathogenesis of many autoimmune and inflammatory diseases. The mechanisms regulating …

α‐Lipoic acid alleviates dextran sulfate sodium salt‐induced ulcerative colitis via modulating the Keap1–Nrf2 signaling pathway and inhibiting ferroptosis

P Jiang, Z Zhai, L Zhao, K Zhang… - Journal of the Science of …, 2024 - Wiley Online Library
BACKGROUND Inflammatory bowel disease (IBD) is a chronically relapsing inflammatory
disease with severe diarrhea, fatigue and weight loss. α‐Lipoic acid (LA), a well‐known …

Revisiting drug–protein interaction prediction: a novel global–local perspective

Z Zhou, Q Liao, J Wei, L Zhuo, X Wu, X Fu… - Bioinformatics, 2024 - academic.oup.com
Motivation Accurate inference of potential Drug-protein interactions (DPIs) aids in
understanding drug mechanisms and developing novel treatments. Existing deep learning …