Biomedical researchers tirelessly seek cutting‐edge technologies to advance disease
diagnosis, drug discovery, and therapeutic interventions, all aimed at enhancing human and …

Chitinase 3-like 1 (also known as CHI3L1 or YKL-40) is a mammalian chitinase that has no
enzymatic activity, but has the ability to bind to chitin, the polymer of N-acetylglucosamine …

Background and Objectives The aim of this study was to identify novel biomarkers for
multiple sclerosis (MS) diagnosis and prognosis, addressing the critical need for specific …

The multifaceted nature of multiple sclerosis requires quantitative biomarkers that can
provide insights related to diverse physiological pathways. To this end, proteomic analysis of …

Establishing biomarkers to predict multiple sclerosis diagnosis and prognosis has been
challenging using a single biomarker approach. We hypothesised that a combination of …

Background Multiple sclerosis is an inflammatory and degenerative disease of the central
nervous system leading to demyelination and axonal loss. Relapsing-remitting multiple …

The potential of combining serum neurofilament light chain (sNfL) and glial fibrillary acidic
protein (sGFAP) levels to predict disability worsening in multiple sclerosis (MS) remains …

Introduction Body fluid markers could be helpful to predict the conversion into clinically
definite multiple sclerosis (MS) in people with a first demyelinating event of the central …

Multiple sclerosis (MS) is a very heterogeneous disease, in terms of clinical presentation,
rate of progression, and response to therapy. Unfortunately, there is a paucity of fluid …

The study aimed to evaluate the effect of high-intensity intermittent exercise (HIIE) on serum
levels of MMP-9 and CHI3L1 in multiple sclerosis. Study group received HIIE twice a week …