[HTML][HTML] Alzheimer's Disease Neuropathological Change in Aged Non-Primate Mammals
I Ferrer - International Journal of Molecular Sciences, 2024 - mdpi.com
Human brain aging is characterized by the production and deposition of β-amyloid (Aβ) in
the form of senile plaques and cerebral amyloid angiopathy and the intracellular …
the form of senile plaques and cerebral amyloid angiopathy and the intracellular …
Addressing the Discrepancies Between Animal Models and Human Alzheimer's Disease Pathology: Implications for Translational Research
Animal models, particularly transgenic mice, are extensively used in Alzheimer's disease
(AD) research to emulate key disease hallmarks, such as amyloid plaques and …
(AD) research to emulate key disease hallmarks, such as amyloid plaques and …
Microbiome alterations are associated with apolipoprotein E mutation in Octodon degus and humans with Alzheimer's disease
Gut microbiome dysbiosis is linked to many neurological disorders including Alzheimer's
disease (AD). A major risk factor for AD is polymorphism in the apolipoprotein E (APOE) …
disease (AD). A major risk factor for AD is polymorphism in the apolipoprotein E (APOE) …
Effect and Mechanism of Rapamycin on Cognitive Deficits in Animal Models of Alzheimer's Disease: A Systematic Review and Meta-analysis of Preclinical Studies
J Cai, D Xie, F Kong, Z Zhai, Z Zhu… - Journal of …, 2024 - content.iospress.com
Background: Alzheimer's disease (AD), the most common form of dementia, remains long-
term and challenging to diagnose. Furthermore, there is currently no medication to …
term and challenging to diagnose. Furthermore, there is currently no medication to …
A New Tool to Study Parkinsonism in the Context of Aging: MPTP Intoxication in a Natural Model of Multimorbidity
L Cuenca, E Pizzichini, VC Gonçalves, M Guillén-Díaz… - 2024 - digitum.um.es
The diurnal rodent Octodon degus (O. degus) is considered an attractive natural model for
Alzheimer's disease and other human age-related features. However, it has not been …
Alzheimer's disease and other human age-related features. However, it has not been …