Acetyl-L-carnitine and Amyotrophic Lateral Sclerosis: Current evidence and potential use
F De Marchi, S Venkatesan, M Saraceno… - CNS & Neurological …, 2024 - ingentaconnect.com
Background: The management of neurodegenerative diseases can be frustrating for
clinicians, given the limited progress of conventional medicine in this context. Aim: For this …
clinicians, given the limited progress of conventional medicine in this context. Aim: For this …
[HTML][HTML] The multifaceted role of the CXC chemokines and receptors signaling axes in ALS pathophysiology
Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disease with complex
genetic basis and still no clear etiology. Multiple intertwined layers of immune system …
genetic basis and still no clear etiology. Multiple intertwined layers of immune system …
[PDF][PDF] TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALS
J Yan, YM Wang, A Hellwig, H Bading - Cell Reports Medicine, 2024 - cell.com
Toxic signaling by extrasynaptic NMDA receptors (eNMDARs) is considered an important
promoter of amyotrophic lateral sclerosis (ALS) disease progression. To exploit this …
promoter of amyotrophic lateral sclerosis (ALS) disease progression. To exploit this …
[PDF][PDF] Neuromuscular organoids model spinal neuromuscular pathologies in C9orf72 amyotrophic lateral sclerosis
C Gao, Q Shi, X Pan, J Chen, Y Zhang, J Lang, S Wen… - Cell Reports, 2024 - cell.com
Hexanucleotide repeat expansions in the C9orf72 gene are the most common cause of
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Due to the lack of trunk …
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Due to the lack of trunk …
Sex-dependent effects of the uncompetitive N-methyl-D-aspartate receptor antagonist REL-1017 in G93A-SOD1 amyotrophic lateral sclerosis mice
M Colognesi, A Shkodra, D Gabbia… - Frontiers in …, 2024 - frontiersin.org
Introduction The pathogenesis of amyotrophic lateral sclerosis (ALS), a fatal
neurodegenerative disease caused by the demise of motor neurons has been linked to …
neurodegenerative disease caused by the demise of motor neurons has been linked to …
Evaluation of carotid Intima-Media Thickness (IMT) in amyotrophic lateral sclerosis disease using ultrasonography
MR Semnani, Z Mirzaasgari, A Ariaei… - Journal of Clinical …, 2024 - Elsevier
Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a progressive
neurodegenerative disease with multi-mechanisms as; inflammation, oxidative stress …
neurodegenerative disease with multi-mechanisms as; inflammation, oxidative stress …
Neurological Disorders and Challenges in Their Theranostics
Neurological disorders encompass multifaceted and heterogeneous ailments that influence
the whole body though the central and peripheral nervous systems. These conditions give …
the whole body though the central and peripheral nervous systems. These conditions give …
Exploring the Role of Endogenous TDP-43 SUMOylation in Mice: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
C Part - 2024 - ruor.uottawa.ca
As the most common motor neuron disease, Amyotrophic lateral sclerosis (ALS) affects
around 4 in every 100,000 people worldwide with reports of increasing prevalence over the …
around 4 in every 100,000 people worldwide with reports of increasing prevalence over the …