Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

Lipid nanoparticles for delivering mRNA therapeutics hold immense promise for the
treatment of a wide range of lung-associated diseases. However, the lack of effective …

The success of personalized medicine in oncology relies on using highly effective and
precise therapeutic modalities such as small interfering RNA (siRNA) and monoclonal …

Messenger RNA (mRNA)‐based therapy has emerged as a powerful, safe, and rapidly
scalable therapeutic approach that involves technologies for both mRNA itself and the …

The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

DNA hydrogels with unique sequence programmability on nucleic acid framework manifest
remarkable attributes, such as high payload capacities, biocompatibility and biosafety. The …

Dendritic cell (DC) maturation is a crucial process for antigen presentation and the initiation
of T cell‐mediated immune responses. Toll‐like receptors play pivotal roles in stimulating …

Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …