Precursor lesions in familial and hereditary pancreatic cancer
Infiltrating ductal adenocarcinoma of the pancreas, referred to here as “pancreatic cancer,” is
one of the deadliest of all of the solid malignancies. The five-year survival rate in the United …
one of the deadliest of all of the solid malignancies. The five-year survival rate in the United …
Long-Term Oncologic Outcome Following Duodenum-Preserving Pancreatic Head Resection for Benign Tumors, Cystic Neoplasms, and Neuroendocrine Tumors …
HG Beger, B Mayer, B Poch - Annals of Surgical Oncology, 2024 - Springer
Background Pancreatoduodenectomy (PD) has a considerable surgical risk for
complications and late metabolic morbidity. Parenchyma-sparing resection of benign tumors …
complications and late metabolic morbidity. Parenchyma-sparing resection of benign tumors …
Gene rearrangement and expression of PRKACA and PRKACB govern morphobiology of pancreatobiliary oncocytic neoplasms
T Itoh, Y Omori, M Seino, K Hirose, F Date, Y Ono… - Modern Pathology, 2024 - Elsevier
Intraductal oncocytic papillary neoplasms (IOPNs) are distinct from intraductal papillary
mucinous neoplasms based on characteristic morphologic and genetic features represented …
mucinous neoplasms based on characteristic morphologic and genetic features represented …
Risk of Recurrence After Surgical Resection for Adenocarcinoma Arising From Intraductal Papillary Mucinous Neoplasia (IPMN) With Patterns of Distribution and …
J Lucocq, J Hawkyard, FP Robertson, B Haugk… - Annals of …, 2024 - journals.lww.com
Objective: This international multicenter cohort study aims to identify recurrence patterns and
treatment of first and second recurrence in a large cohort of patients after pancreatic …
treatment of first and second recurrence in a large cohort of patients after pancreatic …
Identification of spatially-resolved markers of malignant transformation in Intraductal Papillary Mucinous Neoplasms
Abstract The existing Intraductal Papillary Mucinous Neoplasm (IPMN) risk stratification
relies on clinical and histological factors, resulting in inaccuracies and leading to suboptimal …
relies on clinical and histological factors, resulting in inaccuracies and leading to suboptimal …
Neoplastic Progression in Macroscopic Precursor Lesions of the Pancreas
ED Thompson - Archives of Pathology & Laboratory …, 2024 - meridian.allenpress.com
Context.—Macroscopic precursor lesions of the pancreas represent a complex clinical
management problem. Molecular characterization of pancreatic cysts has helped to confirm …
management problem. Molecular characterization of pancreatic cysts has helped to confirm …
Targeting KRAS mutations in pancreatic cancer: opportunities for future strategies
A Linehan, M O'Reilly, R McDermott… - Frontiers in Medicine, 2024 - frontiersin.org
Targeting the RAS pathway remains the holy grail of precision oncology. In the case of
pancreatic ductal adenocarcinomas (PDAC), 90–92% harbor mutations in the oncogene …
pancreatic ductal adenocarcinomas (PDAC), 90–92% harbor mutations in the oncogene …
Pancreatic Cancer Screening among High-risk Individuals
KM Turner, SH Patel - Surgical Clinics, 2024 - surgical.theclinics.com
The incidence of pancreas cancer is estimated to be 66,440 cases in 2024, making it the
10th most common cancer in the United States. 1 Despite its rare nature, mortality rates …
10th most common cancer in the United States. 1 Despite its rare nature, mortality rates …
Molecular Pathology of Pancreatic Cystic Lesions with a Focus on Malignant Progression
Simple Summary Pancreatic cysts are being identified with increasing frequency, and the
prevalence increases with age to 10–25% by the 7th decade of life. They also have the …
prevalence increases with age to 10–25% by the 7th decade of life. They also have the …
Pancreas Cyst Diagnosis and Advances in Cyst Fluid Analysis
T Pollini, L Todeschini, AV Maker - Surgical Clinics, 2024 - surgical.theclinics.com
Pancreatic cystic neoplasms are frequently detected in the general population. Among
these, mucinous cysts, specifically intraductal papillary mucinous neoplasms (IPMN) and …
these, mucinous cysts, specifically intraductal papillary mucinous neoplasms (IPMN) and …