CRISPR/Cas gene editing and delivery systems for cancer therapy
Y Li, S Zhou, Q Wu, C Gong - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
CRISPR/Cas systems stand out because of simplicity, efficiency, and other superiorities,
thus becoming attractive and brilliant gene‐editing tools in biomedical field including cancer …
thus becoming attractive and brilliant gene‐editing tools in biomedical field including cancer …
Metabolic Modulation of Kynurenine Based on Kynureninase-Loaded Nanoparticle Depot Overcomes Tumor Immune Evasion in Cancer Immunotherapy
Evading recognition of immune cells is a well-known strategy of tumors used for their
survival. One of the immune evasion mechanisms is the synthesis of kynurenine (KYN), a …
survival. One of the immune evasion mechanisms is the synthesis of kynurenine (KYN), a …
[HTML][HTML] Nano-revolution in hepatocellular carcinoma: A multidisciplinary odyssey-Are we there yet?
HD Lee, LY Yuan - World Journal of Hepatology, 2024 - ncbi.nlm.nih.gov
In this editorial we comment on the review by Zhou et al reviewing the landscape of
nanomedicine in the treatment of hepatocellular carcinoma (HCC). We focus on the …
nanomedicine in the treatment of hepatocellular carcinoma (HCC). We focus on the …
A Hybrid Nanotube Stamp System in Intracellular Protein Delivery for Cancer Treatment and NMR Analytical Techniques
B Zhang, B Liu, Z Wu, K Oyama, M Ikari… - Analytical …, 2024 - ACS Publications
In contrast to intracellular gene transfer, the direct delivery of expressed proteins is a
significantly challenging yet essential technique for elucidating cellular functions, including …
significantly challenging yet essential technique for elucidating cellular functions, including …
Polymers of functionalized diaminopropionic acid are efficient mediators of active exogenous enzyme delivery into cells
A Romanowska, P Rachubik, A Piwkowska… - Scientific Reports, 2024 - nature.com
Delivery of active protein especially enzyme is one of the major therapeutic challenge.
Replacing or substituted invalid/improper acting protein offer fast and effective treatment of …
Replacing or substituted invalid/improper acting protein offer fast and effective treatment of …
[PDF][PDF] A novel class of mRNA lipid nanoparticles (LNPs) optimized by the chemical evolution approach
F Haase - 2024 - edoc.ub.uni-muenchen.de
Nucleic acid therapeutics have emerged as a groundbreaking advance in modern medicine,
once the molecular structure of nucleic acids was unraveled [1, 2]. This discovery paved the …
once the molecular structure of nucleic acids was unraveled [1, 2]. This discovery paved the …
[引用][C] Novel natural nanosyringes: solving biologics delivery at the cellular level
JRJ Healey - Trends in Biotechnology, 2024 - cell.com
Modern pharmaceuticals are undergoing something of a transformation. In the past few
decades, therapies have become increasingly powerful, but at the cost of complexity. In …
decades, therapies have become increasingly powerful, but at the cost of complexity. In …