Immunomodulatory hydrogels for skin wound healing: cellular targets and design strategy

Y He, Y Cen, M Tian - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Skin wounds significantly impact the global health care system and represent a significant
burden on the economy and society due to their complicated dynamic healing processes …

Metabolic reprogramming in skin wound healing

Z Wang, F Zhao, C Xu, Q Zhang, H Ren… - Burns & …, 2024 - academic.oup.com
Metabolic reprogramming refers to the ability of a cell to alter its metabolism in response to
different stimuli and forms of pressure. It helps cells resist external stress and provides them …

Exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells facilitates diabetic wound healing by restoring keratinocyte autophagy

Y Shi, S Wang, D Liu, Z Wang, Y Zhu, J Li, K Xu… - Burns & …, 2024 - academic.oup.com
Background Refractory diabetic wounds are a common occurrence in patients with diabetes
and epidermis-specific macroautophagy/autophagy impairment has been implicated in their …

Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophagy

Z Lin, L Li, L Chen, C Jin, Y Li, L Yang, C Li… - Acta Pharmacologica …, 2024 - nature.com
Among the numerous complications of diabetes mellitus, diabetic wounds seriously affect
patients' quality of life and result in considerable psychological distress. Promoting blood …

[HTML][HTML] Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation

J He, S Zhou, J Wang, B Sun, D Ni, J Wu… - Journal of …, 2024 - Springer
Background In the inflammatory milieu of diabetic chronic wounds, macrophages undergo
substantial metabolic reprogramming and play a pivotal role in orchestrating immune …

Self-healing hydrogels as injectable implants: Advances in translational wound healing

S Khattak, I Ullah, H Xie, XD Tao, HT Xu… - Coordination Chemistry …, 2024 - Elsevier
Self-healing hydrogels' remarkable dependability and enduring stability have made them
stand out as extremely promising soft materials for tissue engineering. The mechanism …

Association Between Neuroinflammation and Parkinson's Disease: A Comprehensive Mendelian Randomization Study

YN Wang, XY Shi, YP Yin, F Yang, YN Zhang… - Molecular …, 2024 - Springer
The objective of the study is to determine the causal relationship and potential mechanisms
between Parkinson's disease (PD) and neuroinflammatory and neurotoxic mediators. We …

Cathelicidin LL-37 promotes wound healing in diabetic mice by regulating TFEB-dependent autophagy

L Xi, J Du, W Xue, K Shao, X Jiang, W Peng, W Li… - Peptides, 2024 - Elsevier
Diabetic patients often experience impaired wound healing. Human cathelicidin LL-37
possesses various biological functions, such as anti-microbial, anti-inflammatory, and pro …

[HTML][HTML] Multiomics integration-based immunological characterizations of adamantinomatous craniopharyngioma in relation to keratinization

C Xu, J Wu, J Ye, Y Si, J Zhang, B Wu, L Pan, J Fu… - Cell Death & …, 2024 - nature.com
Although adamantinomatous craniopharyngioma (ACP) is a tumour with low histological
malignancy, there are very few therapeutic options other than surgery. ACP has high …

GSDME-mediated keratinocyte pyroptosis participates in the pathogenesis of psoriasis by promoting skin inflammation

Y Li, Y He, F Yang, R Liang, W Xu, Y Li… - British Journal of …, 2024 - academic.oup.com
Objective Psoriasis is a common, chronic inflammatory disease with unclear etiology.
Keratinocytes in psoriasis are susceptible to exogenous triggers that induce inflammatory …