Iron Metabolism and Inflammatory Mediators in Patients with Renal Dysfunction

T Matsuoka, M Abe, H Kobayashi - International Journal of Molecular …, 2024 - mdpi.com
Chronic kidney disease (CKD) affects around 850 million people worldwide, posing
significant challenges in healthcare due to complications like renal anemia, end-stage …

Skeletal Muscle Injury in Chronic Kidney Disease—From Histologic Changes to Molecular Mechanisms and to Novel Therapies

K Heitman, MS Alexander, C Faul - International Journal of Molecular …, 2024 - mdpi.com
Chronic kidney disease (CKD) is associated with significant reductions in lean body mass
and in the mass of various tissues, including skeletal muscle, which causes fatigue and …

Induction of Fenestrae in Human Induced Pluripotent Stem Cell-Derived Endothelial Cells for Disease Modeling

EM Meijer, CGM van Dijk, R Giles, K Gijsen… - … Engineering Part A, 2024 - liebertpub.com
The endothelial linings of capillaries, such as those in the kidney and small intestines,
possess fenestrae that facilitate fluid and exchange of small molecules. Alterations in the …

Design, QSAR methodology, synthesis and assessment of some structurally different xanthone derivatives as selective cox-2 inhibitors for their anti-inflammatory …

R Saikia, K Pathak, A Das, D Tayeng… - Medicinal …, 2024 - ingentaconnect.com
Introduction: Inflammation can be defined as a complex biological response that is produced
by body tissues to harmful agents like pathogens, irritants, and damaged cells and thereby …

The percentage of circulating fibrocytes is associated with increased morbidity of pulmonary hypertension in patients on hemodialysis

X Liu, X Li, J Duan, R Zhang, H Zhang… - Seminars in …, 2024 - Wiley Online Library
Introduction: Pulmonary hypertension (PH) is highly prevalent in patients receiving dialysis.
The precise mechanisms underlying PH in hemodialysis (HD) patients have not been …

Leptospirosis: A dual threat–predisposing risk for renal transplant and trigger for renal transplant dysfunction

JA Ruiz-Pacheco, JE Reyes-Martínez… - Human Immunology, 2024 - Elsevier
Leptospirosis (LTPS) is a bacterial infection that affects humans, often with mild or no
symptoms. It is estimated that approximately 10% of patients with LTPS may experience …

Association of IL-4 (− 590 C/T) and IL-6 (− 174 G/C) gene polymorphism in South Indian CKD patients

V Sevak, R Chinniah, S Pandi… - Egyptian Journal of …, 2024 - Springer
Aim The present study was undertaken to examine the role of IL-4 (− 590 C/T)(rs2243250)
and IL-6 (− 174G/C)(rs1800795) polymorphism and the serum levels of IL-4 and IL-6 in …

[HTML][HTML] Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease

A Hofherr, EL Marin, B Musial, A Seth, T Slidel… - Kidney International …, 2024 - Elsevier
Introduction Inflammation is a significant contributor to cardiorenal morbidity and mortality in
diabetic kidney disease (DKD). The pathophysiological mechanisms linking systemic …

[HTML][HTML] APRI as a predictor of severe dengue fever

AK Jayachandran, V Nelson… - Journal of Family Medicine …, 2024 - journals.lww.com
Objective: 1) To determine the utility of APRI as a predictor of severe dengue. 2) To
determine the association of APRI with length of hospital stay and platelet requirement …

Interleuquina-6 como marcador pronóstico en el fracaso renal agudo y su regulación dependiente de klotho

L González-Lafuente, E Mercado-García… - Nefrología, 2024 - Elsevier
Antecedentes y objetivo En un fracaso renal agudo (FRA) se activa un fuerte componente
inflamatorio como respuesta al daño renal, y uno de los principales mediadores de este …