[HTML][HTML] A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

F Ren, A Aliper, J Chen, H Zhao, S Rao, C Kuppe… - Nature …, 2024 - nature.com
Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high
mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at …

Mendelian randomization study on the causal effect of herpes simplex virus infection on idiopathic pulmonary fibrosis

M Zhang, J Qiu, R Wang - Expert Review of Respiratory Medicine, 2024 - Taylor & Francis
Background Previous observational studies have shown that past infection of herpes
simplex virus (HSV) is associated with idiopathic pulmonary fibrosis (IPF). The present study …

Interstitial lung disease: a review of classification, etiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment

MA Althobiani, AM Russell, J Jacob, Y Ranjan… - Frontiers in …, 2024 - frontiersin.org
Interstitial lung diseases (ILDs) refer to a heterogeneous and complex group of conditions
characterized by inflammation, fibrosis, or both, in the interstitium of the lungs. This results in …

Montelukast Influence on Lung in Experimental Diabetes

C Gales, B Stoica, G Rusu-Zota, M Nechifor - Medicina, 2024 - mdpi.com
Background and Objectives: The influence of montelukast (MK), an antagonist of cysLT1
leukotriene receptors, on lung lesions caused by experimental diabetes was studied …

Therapeutic Strategies for Idiopathic Pulmonary Fibrosis–Thriving Present and Promising Tomorrow

N Gupta, M Paryani, S Patel, A Bariya… - The Journal of …, 2024 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a continuous, progressive, and lethal age‐related
respiratory disease. It is characterized by condensed and rigid lung tissue, which leads to a …

A preoperative use of manual therapy in a patient with idiopathic pulmonary fibrosis awaiting lung transplant: a case report

B Moody Jones, A Walsh, KL Bishop - Physiotherapy Theory and …, 2024 - Taylor & Francis
Introduction This case report describes the outcomes of a patient with idiopathic pulmonary
fibrosis (IPF) treated with manual therapy (MT) in an outpatient physical therapy setting. IPF …

[HTML][HTML] Biomarkers in idiopathic pulmonary fibrosis: Current insight and future direction

Z Zheng, F Peng, Y Zhou - Chinese Medical Journal Pulmonary and Critical …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with
a dismal prognosis. Early diagnosis, accurate prognosis, and personalized therapeutic …

[PDF][PDF] Manual Therapy as an Alternative Treatment Option for Idiopathic Pulmonary Fibrosis: A Case Report

SS Greenberg, SE Moriarty, I Perera, HE Kasper… - Cureus, 2024 - cureus.com
Idiopathic pulmonary fibrosis (IPF) is a type of interstitial lung disease that results in fibrotic
lung tissue leading to symptoms of dyspnea, nonproductive cough, decreased mobility, and …