BV2-derived extracellular vesicles modulate microglia inflammatory profile, neuronal plasticity, and behavioural performances in late adult mice

A Rinaldi, M Balietti, E Principi, M De Luca… - Brain, Behavior, and …, 2024 - Elsevier
Background During aging, both the brain and the immune system undergo a progressive
impairment of physiological functions. Microglia, the immunocompetent cells of the central …

Does concomitant diazepam and ethanol use modulate age-related cognitive decline in mice?

L Carton, C Landmann, F Auger, N Durieux, C Laloux… - Life Sciences, 2024 - Elsevier
Background Concomitant use of alcohol and benzodiazepines are described among elderly,
raising concerns about their combined impact on memory. We aimed to evaluate the long …

Transcriptomic analysis to identify genes associated with hypothalamus vulnerability in aging mice with cognitive decline

X Tian, Z Zhao, J Zhao, D Su, B He, C Shi… - Behavioural Brain …, 2024 - Elsevier
The normal aging process is accompanied by cognitive decline, and previous studies have
indicated the crucial role of the hypothalamus in regulating both aging and cognition …

Effects of Exercise Training and L-Arginine Loaded Chitosan Nanoparticles on Hippocampus Histopathology, β-Secretase Enzyme Function, APP, Tau, Iba1 and …

F Feizolahi, E Arabzadeh, A Sarshin, F Falahi… - Neurotoxicity …, 2024 - Springer
The objective of this study was to evaluate the combined and independent effects of
exercise training and L-Arginine loaded chitosan nanoparticles (LA CNPs) supplementation …

[HTML][HTML] The Effect of Omega-3 Fatty Acid Supplementation and Exercise on Locomotor Activity, Exploratory Activity, and Anxiety-Like Behavior in Adult and Aged Rats

L Gajdošová, B Katrenčíková… - Physiological …, 2024 - pmc.ncbi.nlm.nih.gov
Aging is an inevitable and complex biological process that is associated with a gradual
decline in physiological functions and a higher disease susceptibility. Omega-3 fatty acids …

Blood pressure variability compromises vascular function in middle-aged mice

PJ Mendiola, P O'Herron, K Xie, MW Brands, W Bush… - bioRxiv, 2024 - biorxiv.org
Blood pressure variability (BPV) has emerged as a novel risk factor for cognitive decline and
dementia, independent of alterations in average blood pressure (BP). However, the …

Impact of Chronic Systemic Inflammation on Neuroinflammation, Anxiety, and Memory

E Crain - 2024 - search.proquest.com
Diet-induced obesity in rodent models is associated with brain pathophysiologies including
impaired hippocampal-dependent memory and anxiety-like behavior. Dietary patterns …

Cognitive Changes Induced on Executive Functions Through Video Gameplay

T Johnson - 2024 - search.proquest.com
The purpose of this study was to examine if there is a statistically significant mean score
difference in executive function before and after a 10-day strategy video game training …