Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Cancer is a complex disease resulting from abnormal cell growth that is induced by a
number of genetic and environmental factors. The tumor microenvironment (TME), which …

Peripheral nerves exist in a stable state in adulthood providing a rapid bidirectional
signaling system to control tissue structure and function. However, following injury …

Cancer cells rewire their metabolism to survive during cancer progression. In this context,
tumour metabolic heterogeneity arises and develops in response to diverse environmental …

Cancer patients often experience changes in mental health, prompting an exploration into
whether nerves infiltrating tumors contribute to these alterations by impacting brain …

Tumour innervation is associated with worse patient outcomes in multiple cancers,, which
suggests that it may regulate metastasis. Here we observed that highly metastatic mouse …

Background In recent years, the significance of the nervous system in the tumor
microenvironment has gained increasing attention. The bidirectional communication …

As the field of cancer neuroscience expands, the strategic targeting of interactions between
neurons, cancer cells and other elements in the tumour microenvironment represents a …

Emerging evidence suggests that nerves within the tumor microenvironment play a crucial
role in regulating angiogenesis. Neurotransmitters and neuropeptides released by nerves …

Enteric glia have been recently recognized as key components of the colonic tumor
microenvironment indicating their potential role in colorectal cancer pathogenesis. Although …